Reduced exercise capacity in patients with systemic sclerosis is associated with lower peak tissue oxygen extraction: a cardiovascular magnetic resonance-augmented cardiopulmonary exercise study

Table 4 Exercise metrics for all groups

Variable	SSc	SSc-PAH	NC-PAH	Healthy Controls	p value
Exercise duration (s)	706 ± 150^†	503 ± 166^†‡	592 ± 256^†	913 ± 158	< 0.001
Peak workload* (W)	62 (27–107)^†	37 (21–107)^†‡	52 (18–141)^†	100 (62–168)	< 0.001
Maximum RER*	1.4 (1.1–1.6)^†§	1.2 (1.0–1.4)^†‡	1.2 (1.0–1.6)^†	1.5 (1.1–2.1)	< 0.001

RER respiratory exchange ratio. Normally distributed data displayed as mean ± SD. *Denotes non-normally distributed data shown as median (range). ^†Significant difference between controls and indicated patient groups. ^‡Significant difference between SSc and SSc-PAH groups. ^§significant difference between NC-PAH and the indicated SSc groups

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