Ventricular flow analysis and its association with exertional capacity in repaired tetralogy of Fallot: 4D flow cardiovascular magnetic resonance study

Table 4 Pearson correlation coefficient R of 4D flow parameters and RV remodelling, RV function and CPET parameters in healthy controls and repaired tetralogy of Fallot (rTOF)

	RV direct flow, %	RV residual volume, %	LV direct flow, %	LV residual volume, %	RV peak systolic KEi_EDV, µJ/ml	RV average systolic KEi_EDV, µJ/ml	RV peak E-wave KEi_EDV, µJ/ml	KE discordance
RVEDV/LVEDV ratio	− 0.582*	0.553*	− 0.207^†	0.115	0.091	0.162	0.567*	0.159
RVEF, %	0.629*	− 0.594*	0.177^†	− 0.252*	0.040	− 0.004	− 0.155	− 0.170
Peak VO₂, ml/kg/min	0.118	− 0.069	0.132	0.075	− 0.029	− 0.034	− 0.242^†	− 0.046
Metabolic equivalents	0.118	− 0.070	0.134	0.073	− 0.032	− 0.037	− 0.246^†	− 0.049
% predicted peak VO₂, %	0.214^†	− 0.136	0.095	0.051	− 0.081	− 0.098	− 0.211^†	− 0.094
Anaerobic threshold, %	0.208^†	− 0.160	0.004	0.036	− 0.130	− 0.128	− 0.229^†	− 0.123
VE/VCO₂ slope	− 0.154	0.068	− 0.066	0.029	0.062	0.088	0.197	0.164

CPET cardiopulmonary exercise testing, EDV end-diastolic volume, KE kinetic energy, KE discordance RV/LV systolic KEi_EDV, KEi_EDV kinetic energy normalized to EDV, LV left ventricular, LVEDV left ventricular end-diastolic volume, RV right ventricular, RVEDV right ventricular end-diastolic volume, RVEF right ventricular ejection fraction, VCO₂ carbon dioxide output, VE minute ventilation, VO₂ oxygen uptake
^*Significance level < 0.01; ^†Significance level < 0.05

ISSN: 1532-429X