Evidence-based cardiovascular magnetic resonance cost-effectiveness calculator for the detection of significant coronary artery disease

Table 2 Published and meta-model lifetime discount quality-adjusted life year, costs, and cost-effectiveness results for selected imaging strategies and scenarios

Strategy	Costs	QALYs	ICER
Published Ge et al. [13] results
No imaging	$16,936	12.721	Reference
CMR	$19,273	12.765	$52,000/QALY
CCTA	$19,886	12.765	Dominated by CMR
Meta-model with Ge et al. [13] inputs^A (replication of Ge et al. [13])
No imaging	$19,223	12.160	Reference
CMR	$21,962	12.204	$63,000/QALY
CCTA	$22,578	12.203	Dominated by CMR
Published Genders et al. [20] results for men
No imaging	$6827	11.062	Reference
CCTA	$13,177	11.840	$29,000/QALY
CMR	$14,172	11.840	Dominated by CCTA
Published Genders et al. [20] results for women
No imaging	$7506	12.110	Reference
CCTA	$14,109	12.340	$29,000/QALY
CMR	$15,198	12.330	Dominated by CCTA
Meta-model with selected Genders et al. [20] inputs^B (replication of Genders et al. [20])
No imaging	$12,549	12.844	Reference
CCTA	$14,487	12.889	$42,000/QALY
CMR	$14,289	12.884	Dominated by CCTA
Meta-model with selected Genders et al. [20] inputs except Ge et al. sensitivity/specificity^C
No imaging	$12,549	12.844	Reference
CMR	$13,997	12.885	$34,000/QALY
CCTA	$14,823	12.885	Dominated by CMR

^ACMR sensitivity = 0.89, CMR specificity = 0.87, CMR cost = $807, CCTA sensitivity = 0.90, CCTA specificity = 0.71, CCTA cost (includes FFR for some patients) = $981, age = 62.5 years, coronary angiography cost = $3941, CABG cost = $38,979, PCI cost = $36,556, prevalence of coronary artery disease = 32.4%, proportion male = 53%
^BCMR sensitivity = 0.89, CMR specificity = 0.76, CMR cost = $621, CCTA sensitivity = 0.98, CCTA specificity = 0.89, CCTA cost = $372, age = 60 years, coronary angiograph cost = $2989, CABG cost = $38,217, PCI cost = $6529, prevalence of coronary artery disease = 30.0
^CCMR sensitivity = 0.89, CMR specificity = 0.87, CMR cost = $621, CCTA sensitivity = 0.90, CCTA specificity = 0.71, CCTA cost = $372, age = 60 years, coronary angiograph cost = $2989, CABG cost = $38,217, PCI cost = $6529, prevalence of coronary artery disease = 30.0

ISSN: 1532-429X