Table 1 Baseline patient characteristics
All patients (n = 50) | Low-flow (n = 24) | Normal-flow (n = 26) | p-value | |
|---|---|---|---|---|
Age, years | 71 ± 9 | 72 ± 10 | 70 ± 9 | 0.662 |
Female, n (%) | 21 (42) | 9 (38) | 12 (46) | 0.536 |
Body mass index, kg/m2 | 27 ± 5 | 27 ± 5 | 26 ± 5 | 0.477 |
Moderate AS, n (%) | 6 (12) | 1 (4) | 5 (19) | 0.101 |
Severe AS, n (%) | 44 (88) | 23 (96) | 21 (81) | 0.101 |
Bicuspid valve, n (%) | 19 (38) | 8 (33) | 11 (42) | 0.514 |
Smokers, n (%) | 15 (30) | 10 (42) | 5 (19) | 0.119 |
Pack years | 43 ± 184 | 70 ± 254 | 12 ± 20 | 0.215 |
Hypertension, n (%) | 37 (74) | 20 (83) | 17 (65) | 0.212 |
Dyslipidemia, n (%) | 36 (72) | 17 (71) | 19 (73) | 0.682 |
Diabetes mellitus, n (%) | 11 (22) | 8 (33) | 3 (12) | 0.074 |
AS symptoms | 44 (88) | 21 (88) | 23 (89) | 0.603 |
Vertigo | 17 (34) | 9 (38) | 8 (31) | 0.686 |
Syncope | 7 (14) | 2 (8) | 5 (19) | 0.220 |
NYHA class, n (%) | ||||
I | 2 (4) | 1 (4.2) | 1 (3.8) | 0.302 |
II | 12 (24) | 3 (12.5) | 9 (34.6) | 0.056 |
III | 29 (58) | 17 (70.8) | 12 (46.2) | 0.104 |
IV | 7 (14) | 3 (12.5) | 4 (15.4) | 0.726 |
CCS class, n (%) | ||||
I | 6 (12) | 2 (8.3) | 4 (15.4) | 0.672 |
II | 21 (42) | 8 (33.3) | 13 (50) | 0.187 |
III | 18 (36) | 10 (41.7) | 8 (30.8) | 0.483 |
IV | 5 (10) | 4 (16.7) | 1 (3.8) | 0.143 |
Coronary artery disease, n (%) | 34 (68) | 19 (79) | 15 (58) | 0.204 |
Atrial fibrillation, n (%) | 7 (14) | 6 (25) | 1 (4) | 0.036 |
Lab parameters | ||||
eGFR, ml/min/1.73 m2 | 58 ± 5 | 57 ± 6 | 58 ± 4 | 0.792 |
NT-proBNP, ng/l | 1184 ± 2836 | 1438 ± 3786 | 949 ± 1566 | 0.472 |
Troponin T, ng/l | 15 ± 9 | 17 ± 10 | 14 ± 7 | 0.472 |
Total cholesterole, mg/dl | 176 ± 43 | 168 ± 44 | 183 ± 41 | 0.194 |