False lumen rotational flow and aortic stiffness are associated with aortic growth rate in patients with chronic aortic dissection of the descending aorta: a 4D flow cardiovascular magnetic resonance study

Table 3 Bivariate and multivariate correlation of demographics, anatomical features, and flow dynamics and biomechanics in the false lumen with aortic growth rate

	Bivariate		Multivariate
	R	P-value	Beta	P-value	95% CI
Demographics and clinical data
Age [years]	0.018	0.899
Sex (male)		0.398
Body surface area	0.101	0.494
Systolic blood pressure [mmHg]	0.086	0.566
Diastolic blood pressure [mmHg]	0.071	0.637
Smoking		0.390
Hypertension		0.386
Diabetes mellitus		0.391
Dyslipidaemia		0.396
Mechanical prosthetic aortic valve		0.397
Anticoagulation therapy		0.396
Antiplatelet therapy		0.394
Statin therapy		0.394
Type of aortic dissection		0.481
Anatomical features
Maximum DAo diameter [mm]	0.280	0.042
Dominant entry tear area [cm²]	0.257	0.096	0.371	0.018	[0.130; 1.251]
Local distance of the dominant entry tear [mm]	-0.094	0.513
Thrombus in the false lumen [%]	0.336	0.037	0.293	0.049	[0.000; 0.065]
Flow dynamics in the false lumen
Retrograde systolic flow [mL]	0.165	0.237
Retrograde diastolic flow [mL]	0.102	0.465
Retrograde flow fraction [%]	0.060	0.708
IRF [cm²/s]	0.393	0.006	0.433	0.008	[0.034; 0.202]
WSS [N/m²]	0.279	0.060
KE [mJ]	0.015	0.919
MSDR [cm/s³]	-0.214	0.136
Flow stasis [%]	0.106	0.457
Biomechanics in the false lumen
PWV [m/s]	0.370	0.017	0.360	0.017	[0.031; 0.281]

DAo descending aorta, IRF in-plane rotational flow, KE kinetic energy, MSDR maximum systolic deceleration rate, PWV pulse wave velocity, WSS wall shear stress

ISSN: 1532-429X