Table 2 Changes 1 year after TAVR
Parameter | Pre-TAVR | 1 year Post-TAVR | p-value |
|---|---|---|---|
NYHA class, n (%) | < 0.001 | ||
I | 4 (10.0) | 10 (25.0) | |
II | 10 (25.0) | 23 (57.5) | |
III | 26 (65.0) | 6 (15.0) | |
IV | / | 1 (2.5) | |
NT-proBNP, ng/L | 1452 (590–3249) | 568 (239–1002) | 0.001 |
CITP:MMP1 ratio | 2.1 (1.7) | / | |
6-minute walk test, meters | 249.6 (95.9) | 317.0 (98.6) | 0.001 |
MLHFQ, points | 29.9 (16.1) | 20.1 (18.2) | < 0.001 |
Functional parameters | |||
LVEF, % | 58.7 (45.2–71.4) | 67.1 (56.3–77.5) | 0.002 |
LVEDVI, ml/m2 | 82.9 (65.5–101.8) | 71.3 (64.9–84.7) | 0.018 |
LVESVI, ml/m2 | 33.8 (18.1–52.2) | 22.2 (14.8–32.5) | 0.002 |
LV mass index, g/m2 | 94.9 (22.1) | 77.1 (17.9) | < 0.001 |
GLS, % | − 21.4 (8.0) | − 25.0 (6.4) | < 0.001 |
GCS, % | − 36.9 (14.3) | − 42.6 (11.8) | 0.001 |
LA Es, % | 13.3 (6.3) | 17.8 (6.7) | 0.001 |
LA Ee, % | 5.5 (3.2) | 8.4 (4.6) | 0.001 |
LA Ea, % | 8.2 (4.6) | 9.9 (4.2) | 0.027 |
Tissue characterization | |||
T1 myocardium native, ms | 1310.6 (60.2) | 1288.4 (55.6) | 0.11 |
ECV, % | 27.1 (2.9) | 29.3 (3.3) | 0.005 |
tLV myocardial volume indexed, ml/m2 | 90.3 (21.0) | 73.5 (17.0) | < 0.001 |
Non-invasive LGE, % tLV myocardial volume | 12.0 (6.1) | 10.6 (7.1) | 0.18 |
Non-invasive LGE volume indexed, ml/m2 | 7.6 (5.6–13.4) | 7.1 (4.9–8.9) | 0.007 |
Ischemic LGE, % tLV myocardial volume | 2.5 (6.5) | 2.9 (6.6) | 0.17 |
Ischemic LGE volume indexed, ml/m2 | 2.4 (6.0) | 2.7 (6.0) | 0.17 |
Total LGE, ml/m2 | 9.2 (5.6–14.0) | 7.7 (6.0–13.1) | 0.018 |
LV myocardial volume LGE- indexed, ml/m2 | 75.8 (18.5) | 63.3 (16.4) | < 0.001 |
LV Cellular volume indexed, ml/m2 | 55.2 (13.2) | 45.3 (11.1) | < 0.001 |
LV Matrix volume indexed, ml/m2 | 20.7 (6.1) | 18.8 (5.3) | 0.036 |