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Table 2 CMR characteristics in patients with ES and normal controls

From: Detection and evaluation of myocardial fibrosis in Eisenmenger syndrome using cardiovascular magnetic resonance late gadolinium enhancement and T1 mapping

 

Healthy controls (n = 30)

ES patients (n = 45)

P-value

Left ventricle, LV

 LV EDVI, mL/m2

78 ± 13

82 ± 30

0.512

 LV ESVI, mL/m2

29 ± 7

39 ± 17

0.001

 LVEF, %

62.7 ± 4.0

52.9 ± 7.9

 < 0.001

 LV mass index, g/m2

45 ± 8

565 ± 18

0.002

 LV SVI, mL/m2

31 ± 5

39 ± 12

 < 0.001

Right ventricle, RV

 RV EDVI, mL/m2

73 ± 13

122 ± 57

 < 0.001

 RV ESVI, mL/m2

30 ± 9

78 ± 47

 < 0.001

 RVEF, %

59 ± 7

36 ± 13

 < 0.001

 RV SVI, mL/m2

26 ± 4

41 ± 14

 < 0.001

 RV EDV/LV EDV

0.9 ± 0.1

1.5 ± 0.9

 < 0.001

 RV ESV/LV ESV

1.0 ± 0.2

2.3 ± 1.8

 < 0.001

Diffuse myocardial fibrosis

 Native T1, ms

1209 ± 40

1266 ± 76

 < 0.001

 ECV, %

25.6 ± 2.2

28.6 ± 5.9

0.004

LGE presence, n (%)

 Anterior/inferior VIP

–

43 (95.6%)

–

 Any myocardium*

–

16 (35.6%)

–

 Septum

–

12 (26.7%)

–

 RV myocardium

–

10 (22.2%)

–

 LV myocardium

–

3 (6.7%)

–

 RV trabeculae

–

3 (6.7%)

–

 LV papillary

–

1 (2.2%)

–

  1. ES Eisenmenger syndrome, CMR cardiovascular magnetic resonance, LV left ventricular, RV right ventricular, EDVI end-diastolic volume index, ESVI end-systolic volume index, EF ejection fraction, massi mass index, SVI stroke volume index, ECV extracellular volume, LGE late gadolinium enhancement, VIP ventricular insertion point
  2. *Excluding anterior and inferior VIP
  3. Values in bold indicate P values < 0.05