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Table 4 CMR characteristics and longitudinal changes by ventricular dominance

From: Longitudinal changes in ventricular size and function are associated with death and transplantation late after the Fontan operation

Variable

Dominant ventricle

p-value

LV (n = 83)

RV (n = 73)

Follow up time since first CMR, years Median (IQR)

10.7 (6.4, 14.5)

9.2 (5.8, 14.3)

0.13

Composite outcome

  

0.03

 Listing/Death/Transplant

7 (8.4%)

15 (20.5%)

 

 Free of event

76 (91.6%)

58 (79.5%)

 

Male

51 (61.4%)

49 (67.1%)

0.461

At the first CMR

 Age at CMR, years

19.7 ± 10.0

15.6 ± 8.7

0.008

 Height, cm

155 ± 20

149 ± 24

0.10

 Weight, kg

54.5 ± 19.9

50.0 ± 23.1

0.19

 BSA, m2

1.52 ± 0.37

1.42 ± 0.44

0.14

 EDVI, ml/BSA1.3

88.9 ± 28.6

109.0 ± 43.3

< 0.001

 ESVI, ml/BSA1.3

42.3 ± 20.4

53.8 ± 31.7

0.009

 Massi, g/BSA1.3

63.3 ± 23.9

60.5 ± 22.3

0.46

 EF, %

53.9 ± 10.3

52.7 ± 9.6

0.42

 Mass-to-volume ratio

0.76 ± 0.31

0.62 ± 0.30

0.005

 ESWS, kPa

16.0 ± 5.3

19.7 ± 7.7

0.006

At the last CMR

n = 83b

n = 72

 

 Age at CMR, years

25.7 ± 11.0

21.5 ± 9.8

0.013

 Time between 2 CMRs, years

6.0 ± 4.1

5.7 ± 4.0

0.68

 Median (IQR)

5.5 (2.0, 8.6)

4.8 (2.6, 8.7)

0.62

 BSA, m2

1.70 ± 0.34

1.67 ± 0.41

0.59

 EDVI, ml/BSA1.3

96.7 ± 25.4

117.4 ± 49.1

0.002

 ESVI, ml/BSA1.3

46.4 ± 18.7

64.4 ± 44.8

0.002

 Mass index, g/BSA1.3

54.5 ± 16.3

53.9 ± 20.0

0.86

 EF, %

53.2 ± 8.3

48.3 ± 11.0

0.002

 Mass-to-volume ratio

0.58 ± 0.15

0.49 ± 0.16

< 0.001

 ESWS, kPa

16.6 ± 7.1

21.4 ± 8.0

< 0.001

Annual Change in CMR (last-first)/(years between last and first)

 EDVI, ml/BSA1.3/year

Median (IQR)

1.09 (− 0.69, 3.45)a

0.71 (− 1.61, 2.75)

0.48

 ESVI, ml/BSA1.3/year

Median (IQR)

0.69 (− 0.70, 1.99)a

1.22 (− 0.74, 2.66)a

0.24

 Mass index, g/BSA1.3/year

Median (IQR)

− 1.18 (− 2.98, 0.55)a

− 0.93 (− 3.47, 1.05)a

0.70

 EF, %/year

Median (IQR)

− 0.12 (− 0.98, 0.66)

− 0.62 (− 2.21, 0.27)a

0.02

 Mass-to-volume ratio, /year

Median (IQR)

− 0.02 (− 0.05, 0.01)a

− 0.01 (− 0.03, 0.01)a

0.24

 ESWS, kPa/year

Median (IQR)

0.31 (− 0.37, 0.78)

0.30 (− 0.78, 1.40)

0.81

  1. Bold indicates p-value < 0.05
  2. aIndicates that the change is significantly different from 0
  3. bOne patient had transplant listing prior to their last CMR