Table 4 Univariate Cox proportional hazard models for the primary combined outcome (stroke, TIA, atrial fibrillation, atrial flutter, and intracavitary thrombus) in patients with chronic Chagas cardiomyopathy

Demographic and clinical data¹

 Age (years)

1.03

1.00–1.06

0.022

 Sex (female vs. male)

0.74

0.35–1.53

0.419

 Hypertension

0.97

0.46–2.07

0.955

 Dyslipidemia

1.54

0.67–3.50

0.302

 Smoking

  Never

Reference

Reference

Reference

  Former

1.63

0.72–3.66

0.234

  Current

0.48

0.06–3.61

0.476

CMR-derived parameters

 LV end-diastolic volume index (mL/m²)

1.01

1.00–1.01

< 0.001

 LV end-systolic volume index  (mL/m²)

1.01

1.00–1.01

< 0.001

 LV mass index (g/m²)

1.02

1.01–1.04

< 0.001

 LVEF (%)

0.94

0.92–0.96

< 0.001

 LVEF < 40%

5.65

2.64–12.1

< 0.001

 LV LGE (presence vs. absence)

5.31

1.60–17.61

0.006

 LV LGE mass (g)²

1.73

1.23–2.43

0.001

 LV LGE percentual mass²

1.70

1.18–2.44

0.004

 LV aneurysm (presence vs. absence)

2.20

1.06–4.59

0.034