Table 4 Multivariate Cox analysis for the prediction of composite heart failure endpoint
Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
Age | 1.01 (1.00–1.02) | 0.202 | 1.01 (0.99–1.02) | 0.365 | 1.01 (1.00–1.02) | 0.113 |
Systolic BP | 0.99 (0.98–1.00) | 0.015 | 0.99 (0.98–1.00) | 0.010 | 0.99 (0.98–1.00) | 0.022 |
NYHA class | 1.33 (1.05–1.68) | 0.016 | 1.36 (1.08–1.71) | 0.009 | 1.35 (1.07–1.70) | 0.012 |
Log (NT-proBNP) | 1.18 (0.82–1.72) | 0.374 | 1.19 (0.82–1.72) | 0.361 | 1.25 (0.86–1.81) | 0.241 |
LVEF | 0.99 (0.96–1.01) | 0.234 | 0.99 (0.96–1.01) | 0.309 | 0.98 (0.96–1.01) | 0.126 |
LVEDVI | 1.00 (1.00–1.01) | 0.039 | 1.00 (1.00–1.01) | 0.045 | 1.00 (1.00–1.01) | 0.075 |
RVEF | 1.02 (1.00–1.03) | 0.067 | 1.01 (1.00–1.03) | 0.056 | 1.01 (0.99–1.03) | 0.168 |
LGE present | 1.26 (0.92–1.73) | 0.157 | 1.23 (0.89–1.69) | 0.206 | 1.29 (0.94–1.77) | 0.118 |
LAEDVI | 1.00 (1.00–1.01) | 0.353 | 1.00 (1.00–1.01) | 0.308 | 1.00 (1.00–1.01) | 0.307 |
RAVI min | 1.00 (0.99–1.01) | 0.493 | 1.00 (0.99–1.01) | 0.309 | 1.00 (1.00–1.01) | 0.207 |
RA reservoir strain (per 5% decrease) | 1.16 (1.04–1.30) | 0.008 | … | … | … | … |
RA conduit strain (per 5% decrease) | … | … | 1.40 (1.13–1.74) | 0.002 | … | … |
RA booster strain (per 5% decrease) | … | … | … | … | 1.14 (0.97–1.34) | 0.121 |