Fig. 1

Analysis workflow. Following AI segmentation of the aorta, an automated centerline was calculated (a). Analysis planes were placed to delineate 3 aortic segments (AAo, aortic arch, and DAo) and supra-aortic branches were removed (b). Analysis planes were automatically placed every millimeter along the centerline to determine the direction of forward flow (green) and reverse flow (blue). The velocity at each voxel (Vel) associated with this plane was projected onto the reverse flow vector (Rev) to calculate the reverse flow (c). 2D mean intensity projections of reverse flow were generated (d) and mean voxel-wise reverse flow was calculated for each aortic segment