Systolic reverse flow derived from 4D flow cardiovascular magnetic resonance in bicuspid aortic valve is associated with aortic dilation and aortic valve stenosis: a cross sectional study in 655 subjects

Table 2 Multiple linear regression for systolic and diastolic reverse flow

Reverse flow	MAAD	AS			AR			LVEF	SV	Gender (male)	Age	R²	p-value
Reverse flow	MAAD	Mild	Mod	Severe	Mild	Mod	Severe	LVEF	SV	Gender (male)	Age	R²	p-value
Systolic	3e−4***	0.005***	0.009***	0.01***	0.002***	0.003***	0.006***	1e−4**	5e−5***	− 0.002**	1e−5	0.54	1e−72
Diastolic	− 2e−5	7e−4	− 5−e	7e−4	0.002***	0.003***	0.008***	− 7e−5***	3e−5***	0.002***	5e−5^**	0.39	1e−43

AR, AS, LVEF, SV, gender, age and MAA diameter were included in this model due to significant correlation with aortic reverse flow. The regression coefficients are reported, and coefficient significance is denoted by asterisk. MAAD was a significant contributor to systolic, but not diastolic, reverse flow in the ascending aorta (AAo). p-value legend: *p < 0.05, **p < 0.01, ***p < 0.001

ISSN: 1532-429X