Fig. 3
Meta-regression for percent differences of CMR native T1 in COVID-19 studies. The percentage difference of the means for native T1 in COVID-19 and control groups regresses with the time since the original Covid-19 diagnosis. The studies selected are for adult, non-athletic cohorts which also include native T1 results for a control group scanned under equivalent conditions (i.e. same field strength, scanner, T1 mapping technique). The continuous line and dashed lines correspond to the predicted mean and confidence intervals obtained from a meta-regression model for the ratio of means of native T1 for COVID-19 and control groups. The size of the data points is proportional to the weighs given in the meta-regression analysis. The last name of each study’s first author appears next to the data points. All ratios of means of native T1 were converted to percentage differences for illustration in this figure. The native T1 at the upper bound of its normal range in controls corresponds to an approximately 5% relative to its mean [22, 48,49,50, 75, 76, 78, 80, 83,84,85, 87, 93,94,95]