Fig. 9
Forest plot of the hazard ratio of CFR among patients with CAD. The meta-analysis revealed that a higher CMR-derived CFR was significantly associated with a lower rate of MACE (HR = 0.52 per unit increase; 95% CI, 0.37–0.73; p < 0.001; I2 = 84%, p for heterogeneity < 0.001). CAD coronary artery disease, CFR coronary flow reserve, CI confidence interval, CMR cardiac magnetic resonance, MACE major adverse cardiac events