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Table 2 Lesion iImaging characteristics

From: Relationship between coronary high-intensity plaques on T1-weighted imaging by cardiovascular magnetic resonance and vulnerable plaque features by near-infrared spectroscopy and intravascular ultrasound: a prospective cohort study

 

Overall

n = 62

HIP group

n = 30

Non-HIP group

n = 32

p value

Lesion and procedure

Left anterior descending artery, n (%)

35 (56)

15 (50)

20 (63)

0.321

Right coronary artery, n (%)

13 (21)

6 (20)

7 (22)

0.856

Left circumflex artery, n (%)

14 (23)

9 (30)

5 (16)

0.174

CMR findings

Plaque-to-myocardial signal intensity ratio

1.37 (1.13–1.58)

1.61 (1.43–2.11)

1.14 (1.00–1.26)

 < 0.001

Left ventricular ejection fraction, %

61.6 (54.0–67.4)

63.0 (54.0–66.3)

58.8 (53.9–68.6)

0.746

Left ventricular mass, g

71.1 (59.6–90.8)

74.6 (63.8–99.8)

68.9 (56.8–88.3)

0.335

NIRS findings

MaxLCBI4mm

391 ± 222

500 ± 170

288 ± 218

 < 0.001

MaxLCBI4mm ≥ 400, n (%)

26 (42)

19 (63)

7 (22)

 < 0.001

Lesion LCBI

132 ± 83

170 ± 76

97 ± 74

 < 0.001

IVUS findings

Pull-back length, mm

61.3 ± 24.2

68.5 ± 25.2

54.5 ± 21.5

0.021

Lesion length, mm

20.7 (13.8–33.5)

22.8 (13.4–35.9)

19.1 (14.6–32.6)

0.473

Plaque morphology

Fibrous plaque, n (%)

28 (45)

9 (30)

19 (59)

0.019

Attenuated plaque, n (%)

25 (40)

15 (50)

10 (31)

0.132

Echo-lucent plaque, n (%)

13 (21)

10 (33)

3 (9)

0.018

Calcified plaque, n (%)

34 (55)

17 (57)

17 (53)

0.779

Arc of calcified plaque within maxLCBI4mm, °

23 (0–84)

25 (0–100)

23 (0–70)

0.589

Remodeling index

1.00 ± 0.10

1.03 ± 0.07

0.96 ± 0.11

0.009

Average reference EEM CSA, mm2

11.6 (9.6–14.7)

10.8 (9.0–13.3)

12.4 (10.2–16.6)

0.078

EEM CSA within maxLCBI4mm, mm2

11.9 (9.3–13.7)

10.9 (9.0–13.2)

12.0 (9.5–15.7)

0.426

Lumen CSA within maxLCBI4mm, mm2

3.7 (2.9–5.1)

3.2 (2.6–4.0)

4.3 (3.6–5.7)

0.004

Plaque burden within maxLCBI4mm, %

66 ± 10

69 ± 8

63 ± 10

0.011

  1. HIP group, patients with PMR ≥ 1.4 (n = 30)
  2. Non-HIP group, patients with PMR < 1.4 (n = 32)
  3. CMR, cardiovascular magnetic resonance; CSA, cross-sectional area; EEM, external elastic membrane; HIP, high-intensity plaque; IVUS, intravascular ultrasound; LCBI, lipid-core burden index; maxLCBI4mm, maximum lipid core burden index calculated for every 4-mm segment; NIRS, near infrared spectroscopy