Patients with stage 3 CKD (N = 702) | Propensity-matched patients with eGFR ≥ 60 ml/min/1.73 m2 (N = 702) | p value | |
---|---|---|---|
Demographics | |||
Age, years | 71.4 ± 8.8 | 71.3 ± 8.7 | 0.63 |
Male, n (%) | 492 (70.1) | 299 (55.2) | 1.000 |
BMI, kg/m2 | 26.8 ± 3.2 | 27.3 ± 3.7 | < 0.001 |
Coronary risk factors, n (%) | |||
Diabetes mellitus | 260 (48.0) | 260 (48.0) | 1.000 |
Hypertension | 402 (74.2) | 402 (74.2) | 1.000 |
Dyslipidemia | 316 (58.3) | 315 (58.1) | 0.91 |
Current or previous smoking | 177 (32.7) | 177 (32.7) | 1.000 |
Family history of CAD | 45 (8.3) | 42 (7.7) | 0.78 |
Ten-year risk for fatal CAD (%)* | 2.4 (0.8–5.6) | 2.4 (0.8–5.7) | 0.81 |
Stress CMR | |||
LV ejection fraction, % | 62.7 ± 10.0 | 68.9 ± 11.2 | < 0.001 |
LV end-diastolic volume index, ml/m2 | 62.7 ± 13.6 | 60.1 ± 12.3 | < 0.001 |
LV end-systolic volume index, ml/m2 | 23.0 ± 5.2 | 24.1 ± 5.0 | 0.08 |
Presence of unrecognized MI, n (%) | 91 (16.8) | 66 (12.2) | < 0.001 |
Number of segments of LGE | 0.4 ± 1.1 | 0.2 ± 1.0 | < 0.001 |
Presence of ischemia | 97 (17.9) | 76 (14.0) | < 0.001 |
Number of segments of ischemia | 0.4 ± 1.0 | 0.3 ± 0.9 | < 0.001 |
RPP at baseline, mmHg/beats/min | 9.1 (7.0–11.3) | 8.9 (6.7–11.0) | < 0.001 |
RPP at stress, mmHg/beats/min | 10.5 (8.1–12.6) | 10.2 (7.6–12.5) | < 0.001 |