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Table 2 Baseline and CMR characteristics of the propensity-matched population and of patients with stage 3 CKD and patients with eGFR ≥ 60 ml/min/1.73 m2

From: Safety and incremental prognostic value of stress cardiovascular magnetic resonance in patients with known chronic kidney disease

 

Patients with stage 3 CKD

(N = 702)

Propensity-matched patients with eGFR ≥ 60 ml/min/1.73 m2

(N = 702)

p value

Demographics

   

 Age, years

71.4 ± 8.8

71.3 ± 8.7

0.63

 Male, n (%)

492 (70.1)

299 (55.2)

1.000

 BMI, kg/m2

26.8 ± 3.2

27.3 ± 3.7

 < 0.001

Coronary risk factors, n (%)

   

 Diabetes mellitus

260 (48.0)

260 (48.0)

1.000

 Hypertension

402 (74.2)

402 (74.2)

1.000

 Dyslipidemia

316 (58.3)

315 (58.1)

0.91

 Current or previous smoking

177 (32.7)

177 (32.7)

1.000

 Family history of CAD

45 (8.3)

42 (7.7)

0.78

 Ten-year risk for fatal CAD (%)*

2.4 (0.8–5.6)

2.4 (0.8–5.7)

0.81

Stress CMR

   

 LV ejection fraction, %

62.7 ± 10.0

68.9 ± 11.2

 < 0.001

 LV end-diastolic volume index, ml/m2

62.7 ± 13.6

60.1 ± 12.3

 < 0.001

 LV end-systolic volume index, ml/m2

23.0 ± 5.2

24.1 ± 5.0

0.08

 Presence of unrecognized MI, n (%)

91 (16.8)

66 (12.2)

 < 0.001

 Number of segments of LGE

0.4 ± 1.1

0.2 ± 1.0

 < 0.001

 Presence of ischemia

97 (17.9)

76 (14.0)

 < 0.001

 Number of segments of ischemia

0.4 ± 1.0

0.3 ± 0.9

 < 0.001

 RPP at baseline, mmHg/beats/min

9.1 (7.0–11.3)

8.9 (6.7–11.0)

 < 0.001

 RPP at stress, mmHg/beats/min

10.5 (8.1–12.6)

10.2 (7.6–12.5)

 < 0.001

  1. Values are n (%), mean ± SD, or median (interquartile range)
  2. BMI body mass index; CAD coronary artery disease; CMR cardiovascular magnetic resonance; LGE late gadolinium enhancement; LV left ventricle; MI Myocardial infarction; RPP rate-pressure product (pressure mmHg × Heart rate bpm)/1000; SD standard deviation; RV right ventricle
  3. *Based on a modified SCORE project (https://www.escardio.org/Education/Practice-Tools/CVD-prevention-toolbox/SCORE-Risk-Charts) that did not take into account the total cholesterol level