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Table 3 Univariable analysis of clinical and CMR characteristics for prediction of MACE

From: Safety and incremental prognostic value of stress cardiovascular magnetic resonance in patients with known chronic kidney disease

 

MACE

Cardiovascular Mortality

Hazard Ratio (95% CI)

p value

Hazard Ratio (95% CI)

p value

Age

1.02 (0.99–1.05)

0.14

1.08 (1.03–1.12)

0.001

Male

1.15 (0.68–1.93)

0.61

0.68 (0.37–1.26)

0.22

BMI

1.03 (0.96–1.10)

0.41

0.98 (0.89–1.07)

0.60

Diabetes mellitus

4.39 (2.49–7.71)

 < 0.001

4.87 (2.27–10.5)

 < 0.001

Hypertension

1.44 (0.82–2.53)

0.21

1.94 (0.87–4.35)

0.11

Dyslipidemia

0.66 (0.42–1.03)

0.07

0.56 (0.31–1.01)

0.05

Current or previous smoking

1.61 (0.94–2.75)

0.09

1.05 (0.47–2.35)

0.91

Family history of CAD

1.03 (0.45–2.38)

0.94

1.92 (0.81–4.53)

0.14

eGFR, per 10 units

0.73 (0.50–0.83)

0.012

0.53 (0.37–0.68)

 < 0.001

Time between CKD diagnosis and CMR exam

1.62 (0.91–2.59)

0.19

1.99 (0.91–4.40)

0.10

Dyspnea

2.68 (1.60–4.47)

 < 0.001

6.07 (3.36–11.0)

 < 0.001

LVEF, per 10%

0.88 (0.72–1.10)

0.28

1.22 (0.88–1.70)

0.24

LV end-diastolic volume index, per 10 ml/m2

0.96 (0.81–1.14)

0.64

0.86 (0.68–1.08)

0.19

LV end-systolic volume index, per 10 ml/m2

0.78 (0.50–1.21)

0.27

0.44 (0.25–0.73)

0.002

Presence of unrecognized MI

4.31 (2.74–6.79)

 < 0.001

4.27 (2.35–7.75)

 < 0.001

Number of segments with unrecognized MI

2.09 (1.88–2.33)

 < 0.001

2.15 (1.87–2.47)

 < 0.001

Presence of inducible ischemia

12.5 (7.50–20.8)

 < 0.001

9.76 (5.19–18.4)

 < 0.001

Number of segments with ischemia

1.68 (1.55–1.83)

 < 0.001

1.58 (1.40–1.77)

 < 0.001

  1. Same as Table 1
  2. BMI body mass index; CAD coronary artery disease; CI confidence interval; LV Left ventricle; LVEF left ventricular ejection fraction; MACE major adverse cardiac events; MI myocardial infarction