Table 4 Multivariable Cox regression analysis for the prediction of adverse events
MACE | Cardiovascular mortality | |||
|---|---|---|---|---|
Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | |
Model 1* | ||||
Age | 1.02 (0.99–1.06) | 0.17 | 1.09 (1.05–1.15) | < 0.001 |
Male | 0.86 (0.51–1.48) | 0.59 | 0.80 (0.48–1.46) | 0.67 |
BMI | 1.05 (0.99–1.13) | 0.12 | 1.04 (0.95–1.14) | 0.397 |
Diabetes mellitus | 5.22 (0.88–9.50) | < 0.001 | 8.27 (3.59–19.1) | < 0.001 |
Hypertension | 3.66 (1.99–6.73) | < 0.001 | 5.50 (2.26–13.4) | < 0.001 |
Dyslipidemia | 0.77 (0.51–1.25) | 0.63 | 0.59 (0.30–1.08) | 0.09 |
Current or previous smoking | 2.81 (1.55–5.11) | < 0.001 | 1.36 (0.62–3.09) | 0.28 |
Family history of CAD | 1.08 (0.47–2.46) | 0.78 | 1.90 (0.78–4.50) | 0.35 |
LVEF | 0.92 (0.72–1.19) | 0.54 | 0.87 (0.66–1.22) | 0.68 |
eGFR | 0.83 (0.61–0.97) | 0.03 | 0.71 (0.52–0.89) | 0.02 |
Time between CKD diagnosis and CMR exam | 1.62 (0.91–2.59) | 0.19 | 1.99 (0.91–4.40) | 0.10 |
Model 2† | ||||
Presence of unrecognized MI | 5.07 (3.13–8.21) | < 0.001 | 6.15 (2.98–12.1) | < 0.001 |
Model 2bis† | ||||
Presence of inducible ischemia | 16.4 (8.31–34.2) | < 0.001 | 8.22 (3.08–26.2) | < 0.001 |
Model 3‡ | ||||
Presence of unrecognized MI | 4.67 (2.83–7.68) | < 0.001 | 6.21 (3.10–12.5) | < 0.001 |
Presence of inducible ischemia | 15.5 (7.72–30.9) | < 0.001 | 7.67 (2.61–22.6) | < 0.001 |
Model 4§ | ||||
Presence of unrecognized MI | 4.60 (2.80–7.66) | < 0.001 | 6.02 (2.89–11.8) | < 0.001 |
Number of segments of inducible ischemia | 1.19 (1.10–1.29) | < 0.001 | 1.11 (1.04–1.52) | 0.021 |