Table 1 Clinical and CMR characteristics of overall study population compared to control population
Overall population (n = 42) | Control population (n = 20) | P value | |
|---|---|---|---|
Age (± SD) | 48.1 ± 15.4 | 53.3 ± 22.5 | 0.745 |
Male gender (%) | 21 (50%) | 7 (35%) | 0.004 |
BMI (± SD) | 26.4 ± 7.1 | 24.2 ± 3.5 | 0.234 |
BSA (m2 ± SD) | 1.8 ± 0.2 | 1.7 ± 0.3 | 0.412 |
EDV (ml ± SD) | 187 ± 55.9 | 118 ± 39.2 | 0.003 |
EDVi (ml/m2 ± SD) | 101 ± 28.9 | 61.2 ± 17.3 | 0.003 |
ESV (ml ± SD) | 82.1 ± 30.6 | 40.1 ± 21.5 | 0.004 |
EF (% ± SD) | 56.5 ± 7.9 | 60.2 ± 8.3 | 0.097 |
LV mass (g/m2 ± SD) | 63.9 ± 15.4 | 62.1 ± 15.2 | 0.874 |
MAD length (mm ± SD) | 9.3 ± 4.1 | – | |
MR | – | ||
– Mild | 7 (16%) | ||
– Moderate | 25 (60%) | ||
– Severe | 10 (24%) | ||
Native T1 relaxation times (ms ± SD)) | |||
– Anterior wall | 1015 ± 91 | 1005 ± 101 | 0.154 |
– Anterolateral wall | 1047 ± 70 | 994 ± 113 | 0.254 |
– Inferolateral wall | 1083 ± 65 | 1001 ± 55 | 0.423 |
– Inferior wall | 1101 ± 64 | 974 ± 64 | 0.041 |
– Inferoseptal wall | 1074 ± 56 | 978 ± 85 | 0.078 |
– Anteroseptal wall | 1063 ± 46 | 1011 ± 62 | 0.456 |
– Mean | 1097 ± 45 | 1010 ± 26 | 0.002 |
ECV (% ± SD) | |||
– Anterior wall | 0.27 ± 0.04 | 0.25 ± 0.04 | 0.041 |
– Anterolateral wall | 0.29 ± 0.04 | 0.26 ± 0.04 | 0.004 |
– Inferolatera wall | 0.30 ± 0.05 | 0.25 ± 0.04 | 0.005 |
– Inferior wall | 0.30 ± 0.03 | 0.26 ± 0.04 | 0.001 |
– Inferoseptal wall | 0.29 ± 0.04 | 0.26 ± 0.03 | 0.004 |
– Anteroseptal wall | 0.30 ± 0.03 | 0.25 ± 0.04 | 0.002 |
– Mean | 0.30 ± 0.03 | 0.25 ± 0.04 | 0.022 |
GLS (± SD) | − 25.8 ± 8.7 | − 26.7 ± 9.4 | 0.256 |
LS basal (± SD) | |||
– Anterior wall | − 21.2 ± 4.5 | − 22.8 ± 10.6 | 0.771 |
– Anterolateral wall | − 27.2 ± 10.5 | − 25.6 ± 6.3 | 0.715 |
– Inferolateral wall | − 20.0 ± 8.4 | − 24.6 ± 7.8 | 0.087 |
– Inferior wall | − 20.7 ± 7.5 | − 24.4 ± 9.6 | 0.047 |
– Inferoseptal wall | − 17.6 ± 9.4 | − 18.8 ± 9.5 | 0.457 |
– Anteroseptal wall | − 22.1 ± 4.5 | − 22.5 ± 9.6 | 0.541 |
– Mean | − 22.1 ± 6.7 | − 25.5 ± 11.4 | 0.521 |
LS mid–wall (± SD) | |||
– Anterior wall | − 21.8 ± 11.2 | − 22.53 ± 7.6 | 0.771 |
– Anterolateral wall | − 22.7 ± 9.1 | − 26.7 ± 11.6 | 0.715 |
– Inferolateral wall | − 25.7 ± 7.3 | − 22.9 ± 9.7 | 0.087 |
– Inferior wall | − 21.9 ± 9.9 | − 24.8 ± 7.5 | 0.087 |
– Inferoseptal wall | − 25.7 ± 8.3 | − 27.1 ± 6.7 | 0.457 |
– Anteroseptal wall | − 22.7 ± 9.1 | − 18.9 ± 9.1 | 0.541 |
– Mean | − 23.5 ± 8.7 | − 22.1 ± 7.8 | 0.521 |
LS apical (± SD) | |||
– Anterior wall | − 28.7 ± 14.5 | − 27.9 ± 9.6 | 0.715 |
– Septal wall | − 26.7 ± 11.4 | − 33.2 ± 19.0 | 0.287 |
– Lateral wall | − 23.4 ± 8.1 | − 21.0 ± 13.9 | 0.474 |
– Inferior wall | − 28.0 ± 12.6 | − 34.8 ± 15.5 | 0.457 |
– Mean | − 25.6 ± 12.9 | − 28.3 ± 18.0 | 0.541 |
CS basal (± SD) | |||
– Anterior wall | − 25.1 ± 4.1 | − 26.7 ± 4.7 | 0.871 |
– Anterolateral wall | − 27.1 ± 5.1 | − 24.1 ± 5.1 | 0.215 |
– Inferolateral wall | − 24.2 ± 5.8 | − 27.1 ± 5.4 | 0.451 |
– Inferior wall | − 19.7 ± 5.4 | − 27.6 ± 7.2 | 0.021 |
– Inferoseptal wall | − 23.4 ± 8.1 | − 27.5 ± 5.5 | 0.457 |
– Anteroseptal wall | − 22.4 ± 7.0 | − 24.5 ± 5.8 | 0.541 |
– Mean | − 24.2 ± 4.5 | − 25.6 ± 4.5 | 0.521 |
CS mid-ventricular (± SD) | |||
– Anterior wall | − 20.8 ± 4.2 | − 21.5 ± 5.6 | 0.871 |
– Anterolateral wall | − 21.2 ± 5.5 | − 22.5 ± 6.7 | 0.215 |
– Inferolateral wall | − 22.9 ± 7.5 | − 26.4 ± 7.7 | 0.048 |
– Inferior wall | − 16.1 ± 7.7 | − 22.6 ± 3.6 | 0.021 |
– Inferoseptal wall | − 20.8 ± 6.1 | − 21.5 ± 7.6 | 0.457 |
– Anteroseptal wall | − 21.5 ± 7.9 | − 22.5 ± 6.8 | 0.541 |
– Mean | − 20.5 ± 4.5 | − 21.5 ± 5.6 | 0.52 |
CS apical (± SD) | |||
– Anterior wall | − 28.6 ± 12.2 | − 29.7 ± 11.5 | 0.401 |
– Septal wall | − 29.4 ± 21.0 | − 30.5 ± 5.2 | 0.782 |
– Inferior wall | − 32.4 ± 13.7 | − 28.7 ± 12.5 | 0.094 |
– Lateral wall | − 32.7 ± 13.1 | − 35.6 ± 12.5 | 0.357 |
– Mean | − 28.1 ± 6.8 | − 32.5 ± 11.5 | 0.541 |