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Table 1 Baseline patient characteristics

From: Cardiac reverse remodeling in primary mitral regurgitation: mitral valve replacement vs. mitral valve repair

 

Control

(n = 20)

Repair

(n = 30)

Replace

(n = 22)

P-values

All groups

Control vs Repair

Control vs Replace

Repair vs Replace

Male

11 (55%)

24 (80%)

16 (73%)

0.186

   

Age (years)

64 ± 18

67 ± 11

66 ± 10

0.935

   

Duration to follow-up (days)*

233 ± 8

188 ± 27

194 ± 25

0.001

0.001

0.008

1

BMI (kg/m2)

24.1 ± 3.3

26.2 ± 3.8

25.3 ± 5.0

0.275

   

BSA (m2)

1.8 ± 0.2

1.9 ± 0.2

1.9 ± 0.2

0.414

   

Systolic BP (mm/Hg)

125 ± 25

125 ± 15

125 ± 13

1

   

Diastolic BP (mm/Hg)

73 ± 16

77 ± 13

77 ± 10

0.54

   

Heart rate (bpm)

71 ± 10

72 ± 15

72 ± 13

0.885

   

6MWT distance (m)

393 ± 118

365 ± 103

358 ± 79

0.485

   

NYHA functional class

 I

15 (75%)

8 (27%)

4 (18%)

0.001

0.003

0.001

0.256

 II

4 (20%)

16 (53%)

9 (41%)

 III

1 (5%)

6 (20%)

9 (41%)

 IV

0

0

0

Aetiology

Leaflet affected

PMVL

12 (60%)

26 (87%)

12 (54%)

0.027

0.149

0.332

0.014

AMVL

1 (5%)

1 (3%)

5 (23%)

Bi-leaflet

7 (35%)

3 (10%)

5 (23%)

Presence of flail leaflet

4 (20%)

8 (27%)

7 (32%)

0.703

   

Surgical risk scores

 Log Euro

5.6 ± 4.7

4.7 ± 3.5

3.7 ± 2.4

0.736

   

 Log Euro II

1.5 ± 1.4

1.4 ± 1.0

1.6 ± 1.2

0.523

   

 STS mortality

1.5 ± 1.6

1.2 ± 1.2

1.9 ± 1.6

0.076

   

 STS mortality/morbidity

11.8 ± 7.1

9.5 ± 4.9

13.2 ± 5.9

0.053

   

Comorbidities

 Smoking History

7 (35%)

14 (47%)

8 (36%)

0.713

   

 Diabetes mellitus

2 (10%)

1 (3%)

1 (5%)

0.679

   

 Hypertension

4 (20%)

11 (37%)

6 (27%)

0.486

   

 Atrial fibrillation

4 (20%)

16 (53%)

13 (59%)

0.021

0.022

0.014

0.781

 Prior myocardial infarction

1 (5%)

0

1 (5%)

0.507

   

 Prior PCI

2 (10%)

0

1 (5%)

0.183

   

 Prior Stroke

1 (5%)

0

0

0.278

   

 Prior TIA

1 (5%)

1 (3%)

1 (5%)

1

   

 COPD

2 (10%)

1 (3%)

2 (9%)

0.599

   

 Chronic Kidney Disease

1 (5%)

0

1 (5%)

0.507

   

 Haemoglobin (g/L)

137 ± 11

143 ± 10

140 ± 14

0.15

   

 Creatinine (umol/L)

79 ± 14

81 ± 18

88 ± 20

0.244

   
  1. *Duration of time until repeat CMR imaging after either surgical intervention or baseline CMR in control group. 6MWT: 6-min walk test; AMVL: anterior mitral valve leaflet; BMI: body mass index; BP: blood pressure; BPM: beats per minute; BSA: body surface area; COPD: chronic obstructive pulmonary disease; NYHA: New York Heart Association; PCI: percutaneous coronary intervention; PMVL: posterior mitral valve leaflet; TIA: transient ischaemic attack; STS: society of thoracic surgeons