Fig. 12
From: Modeling of factors affecting late gadolinium enhancement kinetics in MRI of cardiac amyloid
Representative display of user interface of interactive program used for simulation of contrast enhancement kinetics (Appendix 2), incorporating 3-compartment model in Fig. 2. Default values for different model parameters can be entered in windows at left and scaled with adjacent interactive sliders. Resulting calculated variables are displayed in the graphs at the right, including: serial concentrations of contrast agent in blood, reference myocardium and “scar” or amyloid deposits (top left); corresponding serial T1 values (bottom left); serial T1 differences of myocardium with blood (top right); and serial longitudinal magnetization values (proportional to signal) for PSIR imaging set to null reference myocardium (bottom right). Some T1 data extracted from Fig. 2 of [1] are also displayed, for comparison with model results