Table 5 Cox Regression Models for the secondary endpoint of all-cause mortality
Death | Univariable analyses | Multivariable model 3a Imaging parameter without RV GLS | Multivariable model 3b Imaging parameter with additional RV GLS | Multivariable model 3c Imaging parameter with RV GLS instead LV GLS | ||||
|---|---|---|---|---|---|---|---|---|
HR (95% CI) | p value | HRadjusted (95% CI) | p value | HRadjusted (95% CI) | p value | HRadjusted (95% CI) | p value | |
Clinical characteristics | ||||||||
Age [years] | 1.05 (1.03–1.07) | < 0.001 | ||||||
Gender [male] | 0.53 (0.29–0.97) | 0.040 | ||||||
Troponin peaka [ng/l] | 1.00 (0.99–1.00) | 0.173 | ||||||
NT-proBNPa [log pg/ml] | 5.01 (1.83–13.7) | 0.002 | ||||||
CMR LGE | ||||||||
LV LGE present | 1.22 (0.63–2.35) | 0.551 | ||||||
LV LGE involves insertion points | 1.38 (0.66–2.92) | 0.394 | ||||||
LV LGE extent FWHM [g] | 1.03 (0.99–1.07) | 0.153 | ||||||
RV LGE presenta | 1.41 (0.54–3.65) | 0.481 | ||||||
CMR ejection fraction | ||||||||
LV EF [%] | 0.97 (0.95–0.99) | < 0.001 | 1.00 (0.96–1.04) | 0.951 | 1.00 (0.96–1.04) | 0.935 | 0.98 (0.96–1.01) | 0.283 |
RV EF [%] | 0.96 (0.94–0.98) | 0.001 | 0.98 (0.94–1.01) | 0.215 | 0.98 (0.95–1.02) | 0.346 | 0.98 (0.95–1.02) | 0.348 |
CMR feature tracking | ||||||||
LV GLS [%] | 1.14 (1.06–1.21) | < 0.001 | 1.08 (0.93–1.24) | 0.310 | 1.06 (0.92–1.23) | 0.393 | ||
LV GCS [%] | 1.10 (1.04–1.17) | 0.001 | ||||||
LV GRS [%] | 0.95 (0.92–0.98) | 0.001 | ||||||
RV GLS [%] | 1.07 (1.02–1.12) | 0.004 | 1.02 (0.96–1.09) | 0.526 | 1.03 (0.96–1.09) | 0.405 | ||
Model Chi-Square | 15.2 | 15.9 | 14.9 | |||||
Df | 3 | 4 | 3 | |||||
p value | 0.002 | 0.003 | 0.002 | |||||
−2 Log-Likelihood | 440.0 | 439.6 | 440.8 | |||||
p-value vs. model without RV GLS | 0.528 | 0.408 | ||||||