Predictive value of cardiac magnetic resonance right ventricular longitudinal strain in patients with suspected myocarditis

Table 6 Univariable Cox Regression for the secondary endpoints of sustained VT and recurrent myocarditis

	Sustained VT Univariable analyses		Recurrent myocarditis Univariable analyses
	HR (95% CI)	p value	HR (95% CI)	p value
Clinical characteristics
Age [years]	1.00 (0.98–1.03)	0.742	0.94 (0.91–0.98)	0.002
Gender [male]	0.80 (0.40–1.59)	0.523	1.31 (0.46–3.78)	0.614
Troponin T peak^a [ng/l]	1.00 (0.99–1.00)	0.266	1.00 (1.00–1.00)	0.301
NT-proBNP^a [log pg/ml]	1.27 (0.54–2.99)	0.584	0.70 (0.20–2.46)	0.576
CMR LGE
LV LGE present	2.47 (1.18–4.54)	0.012	2.30 (0.66–8.08)	0.194
LV LGE involves insertion points	1.50 (0.67–3.34)	0.320	0.70 (0.16–3.11)	0.641
LV LGE extent FWHM [g]	1.07 (1.05–1.10)	< 0.001	1.03 (0.97–1.09)	0.393
RV LGE present^a	2.48 (0.96–6.42)	0.061	1.21 (0.32–4.58)	0.783
CMR ejection fraction
LV EF [%]	0.96 (0.94–0.98)	< 0.001	1.07 (1.02–1.13)	0.009
RV EF [%]	0.95 (0.93–0.97)	< 0.001	1.04 (0.99–1.09)	0.106
CMR feature tracking
LV GLS [%]	1.13 (1.05–1.21)	0.002	0.82 (0.71–0.95)	0.009
LV GCS [%]	1.13 (1.06–1.21)	< 0.001	0.86 (0.76–0.97)	0.014
LV GRS [%]	0.93 (0.90–0.97)	< 0.001	1.06 (1.01–1.11)	0.017
RV GLS [%]	1.02 (0.96–1.08)	0.509	0.95 (0.86–1.04)	0.258

CI: confidence intervals; EF: ejection fraction; FWHM: full width half max; GCS/GLS/GRS: global circumferential/longitudinal/radial strain; HR: Hazard ratio; LGE: late gadolinium enhancement; LV: left ventricle; NT-proBNP: N-terminal pro-hormone brain natriuretic peptide; RV: right ventricle; VT: ventricular tachycardia
^aVariables with > 20% missing values. Troponin was available in 338 (51.3%) patients. NT-proBNP was available in 159 (24.1%) of patients. RV LGE was not assessable in 270 (41%) of patients

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