Effect of concomitant atrial septal defect on left ventricular function in adult patients with unrepaired Ebstein’s anomaly: a cardiovascular magnetic resonance imaging study

Table 2 CMR Parameters between Normal Individuals, ASD Patients, EA Patients without or with ASD

	Normal n = 40	ASD n = 35	EA without ASD n = 76	EA with ASD n = 31	p value
LVEDVI, ml/m²	76 (72–81)	70 (64–76)	75 (67–86)	63 (54–80)^*‡	0.006
LVESVI, ml/m²	28 (26–30)	29 (23–37)	33 (26–39)^*	31 (27–38)	0.078
LVSVI, ml/m²	49 ± 5.5	39 ± 12^*	44 ± 12	34 ± 9.4^*‡	< 0.001
LVEF, %	64 (61–65)	59(49–63)^*	57 (53–62)^*	50 (45–55)^*‡	< 0.001
RVEDVI, ml/m²	62 (58–69)	185 (143–219)^*	155 (114–199)^*	205 (168–277)^*‡	< 0.001
RVESVI, ml/m²	28 (24–31)	108 (86–144)^*	95 (64–137)^*	129 (91–193)^*‡	< 0.001
RVSVI, ml/m²	35 (31–40)	67 (45–87)^*	58 (42–73)^*	60 (41–89)^*	0.666
RVEF, %	55 (52–60)	37 (25–47)^*	39 (29–48)^*	34 (22–42)^*‡	< 0.001
RVEDV/LVEDV	0.84 (0.8–0.9)	2.7 (2.1–3.3)^*	2.0 (1.4–2.9)^*	3.4 (2.4–4.6)^*‡	< 0.001

Data given as the mean ± SD or median (25th, 75th percentile), p value for trend between groups. Pairwise comparisons using Bonferroni correction: *p < 0.05 vs controls; ^‡p < 0.05 vs EA without ASD;. LV, left ventricular; RV, right ventricular; EDV, end diastolic volume; ESV, end systolic volume; SV, stroke volume; EF, ejection fraction; I, indexed to BSA

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