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Table 2 Findings by cardiac magnetic resonance in eosinophilic myocarditis with comparison of patients with and without myocardial necrosis on histopathology

From: Cardiac magnetic resonance in histologically proven eosinophilic myocarditis

 

All patients (n = 15)

NEM (n = 6)

Non-NEM (n = 9)

p-value

Ventricular volumes, function, wall thickness, and pericardium

 LV end-diastolic volume, ml/m2

107 ± 32

121 ± 41

98 ± 21

0.231

 LV ejection fraction, %

40 ± 14

33 ± 16

45 ± 12

0.144

 LV maximal wall thickness, mm

12.7 (11.1–14.6)

13.6 (13.1–15.1)

11.2 (10.9–12.7)

0.111

 LV mass, g/m2

72 (63–88)

88 (75–101)

68 (58–72)

0.036

 RV end-diastolic volume, ml/m2, n = 14/6/8

102 ± 25

112 ± 35

94 ± 12

0.247

 RV ejection fraction, % n = 14/6/8

42 ± 14

35 ± 14

49 ± 7.5

0.037

 RV free wall maximal thickness, mm

3.9 (3.2–4.2)

4.0 (3.3–4.2)

3.6 (3.3–4.1)

0.679

 Pericardial effusiona

8 (53)

2 (33)

6 (67)

0.315

 Presence of LV thrombus, n

2 (13)

1 (17)

1 (11)

1.000

 Presence of RV thrombus, n

1 (7)

1 (17)

0

0.400

 

n = 14

n = 6

n = 8

 

Late gadolinium enhancement (LGE) imagingb

 Presence of LV LGE

13 (93)

6 (100)

7 (88)

1.000

 Presence of RV free wall LGE

7 (50)

5 (83)

2 (25)

0.103

 LV segments with LGE, n

11 ± 4

15 ± 2

9 ± 3

0.003

  With subendocardial involvement, n

5 ± 3

7 ± 1

3 ± 1

< 0.001

  With mid-wall/subepicardial involvement, n

3 ± 2

2 ± 2

3 ± 2

0.214

  With transmural involvement, n

4 ± 3

6 ± 3

3 ± 2

0.047

  With septal involvement, n

5 (4–5)

5 (5–5)

4 (3–5)

0.017

 Wide-spread subendocardial LGE, nc

7 (54)

5 (83)

2 (29)

0.103

 LV LGE mass, %

23 ± 15

32 ± 17

15 ± 7.7

0.0496

 Multifocal

13 (100)

6 (100)

7 (100)

NA

  1. Data are numbers (%) of cases, means ± standard deviation, or medians (interquartile range)
  2. LV left ventricular, NEM necrotizing eosinophilic myocarditis, RV right ventricular
  3. a> 5 mm effusion anterior to right ventricular wall
  4. bAdministration of gadolinium was considered contraindicated in 1 patient
  5. c≥ 4 adjacent segments