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Table 3 Treatment and clinical outcome of patients with eosinophilic myocarditis with and without cardiac magnetic resonance (CMR) imaging at presentation

From: Cardiac magnetic resonance in histologically proven eosinophilic myocarditis

 

All

n = 27

CMR

n = 15

No CMR

n = 12

p-value

Anti-inflammatory drugs, n (%)

 Corticosteroid

24 (89)

14 (93)

10 (83)

0.569

 Azathioprine

3 (11)

2 (13)

1 (8)

1.000

 Methotrexate

1 (4)

1 (7)

0

1.000

 Cyclosporine

2 (7)

0

2 (17)

0.188

Need for circulatory support

13 (48)

7 (47)

6 (50)

0.863

 Inotropes, n (%)

13 (48)

7 (47)

6 (50)

0.863

 Mechanical (ECMO), n (%)

5 (19)

3 (20)

2 (17)

1.000

Device therapy, n (%)

 Temporary pacing

3 (11)

3 (20)

0

0.231

 Permanent pacemaker (no CRT-D)

2 (7)

1 (7)

1 (8)

1.000

 CRT-D

3 (11)

2 (13)

1 (8)

1.000

Outcome

 Follow-up time, ya

3.8 (0.7–8.5)

3.6 (1.1–7.0)

4.7 (0.3–11.0)

0.755

  Cardiac death

5 (19)

1 (7)

4 (33)

0.139

  VF or sustained VT

2 (8)

2 (14)

0

1.000

   Transplantation

1 (4)

0

1 (8)

0.444

  1. Data are numbers (%) of cases, means ± standard deviation, or medians (interquartile range)
  2. CMR cardiac magnetic resonance, ECMO extra-corporeal membrane oxygenation, CRT-D cardiac resyncronization therapy and implantable cardioverter-defibrillator, VF ventricular fibrillation, VT ventricular tachycardia
  3. aFrom symptom onset to event or last out-patient follow-up until May 2020