- Meeting abstract
- Open Access
301 Accurate quantification of aortic regurgitation: comparison of MRI with doppler echocardiography
© Sekar et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Aortic Valve
- Aortic Regurgitation
- Doppler Echocardiography
- Imaging Location
- Phase Contrast Image
Echocardiography is the most widely used imaging modality for assessment of aortic regurgitation. Phase contrast MRI may also be used to quantify aortic regurgitation, but no standard imaging location has been identified on MRI. The purpose of this study is to determine which imaging location (at, above, or below the aortic valve) on phase contrast MRI best correlates with echocardiography.
A retrospective chart review identified 71 patients (52 male, 19 female) who were determined to have aortic regurgitation on PC-MRI. Phase contrast images were analyzed using the ARGUS program (Siemens). Regions of Interest (ROI) were manually defined around flow jets for images at the aortic valve as well as 6 mm above and below the aortic valve. Forward and reverse volumes were measured from these ROIs. To verify the internal consistency of the ARGUS program measurements left ventricular cine true FISP images were used and ROIs were manually drawn around the endocardium in order to calculate the end diastolic volume (EDV) and end systolic volume (ESV). The difference in these two volumes was compared to the forward volume at the valve. Of the 71 patients who underwent PC-MRI, quantitative data were obtained on echocardiogram for 23 patients using the Velocity Time Integral.
Mean volume Echo (mL)
Mean volume MRI (mL)
Regurgitant fraction. In this retrospective study of 71 patients, Phase Contrast MRI at varying imaging planes was compared with Echocardiography to measure aortic regurgitation. Regurgitant Fraction on MRI correlates best with Echo when the numerator is measured below the aortic valve.
p (two tailed t-test)
The Argus program is internally consistent and can be used to provide quantitative data from PC-MRI. The level in relation to the aortic valve is important in quantifying aortic regurgitation with MRI. The best correlation with echocardiography occurs when the regurgitant volume is quantified at the aortic valve, and when the regurgitant fraction is calculated with the reverse volume quantified below the valve.
This article is published under license to BioMed Central Ltd.