- Meeting abstract
- Open Access
307 MRI-guided atrio-ventricular node ablation in swine models using MRI tracking
© Schmidt et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Right Ventricle
- Swine Model
- Node Block
- Atrium Junction
- Slow Drip
MRI-guided navigation, Electro-Physiological (EP) voltage mapping of the left ventricle, as well as mapping and Radio-Frequency Ablation (RFA) at the Pulmonary Vein/Left Atrium junction, were previously demonstrated in swine models (references [1–3]). This study is an extension of the MRI-tracked technique, using simultaneous multiple-catheter tracking, to locate, perform RFA and verify ablation of the Atrio-Ventricular (AV) node, with electrical and MRI signatures. AV node ablation is a treatment component for types of arrhythmia, usually followed by pacemaker implantation.
To perform AV node ablation in an MRI scanner, utilizing clinical grade MRI-tracked catheters. To demonstrate MRI-guidance advantages in anatomic imaging and in the rapid post-delivery monitoring of the extent of ablation injury.
Locating the AV node was a lengthy procedure (> 20 minutes). Catheter voltage (Figure 1B) and high-resolution 3D MDE (Figure 1C) demonstrated the AV node ablation rapidly (< 2 minutes). Histology verified well-positioned ablation lesions. Total node blockage was achieved in 2 pigs, partial in 1 pig.
MRI-tracked AV node ablation, simultaneously visualizing 3 catheters at 12–15 frames per second, is feasible.