111 Detection of changes in myocardial blood flow and volume: a CMR study in a canine model of coronary artery stenosis
© McCommis et al; licensee BioMed Central Ltd. 2008
Published: 22 October 2008
Quantification of both myocardial blood flow (MBF) and myocardial blood volume (MBV) may provide critical information on coronary artery diseases. We have recently developed fast mapping techniques for quantifying both perfusion parameters with the CMR first-pass dynamic imaging approach and an intravascular contrast agent. The purpose of this study is to evaluate the techniques in the assessment of changes in MBF and MBV that occur with differing severities of coronary artery stenosis during Dipyridamole or Dobutamine induced hyperemia.
First-pass perfusion CMR allows for fast evaluation of MBF/MBV changes during pharmacologically induced hyperemia. Measurements of both MBF and MBV may allow for more comprehensive diagnoses of coronary artery stenosis and better treatment planning.
- Goldstein TA: Magn Reson Med. 2006, 56: 439-45. 10.1002/mrm.20950.View ArticlePubMedGoogle Scholar
- Goldstein TA: Proceedings of the International Society of Magnetic Resonance in Medicine, Seattle, WA. 2006, 3573-Google Scholar
- Sambuceti G: Am J of Cardiol. 1993, 72: 538-43. 10.1016/0002-9149(93)90348-G.View ArticleGoogle Scholar
- Sambuceti G: Circulation. 1994, 90: 1696-1705.View ArticlePubMedGoogle Scholar
- Wu JC: J Nucl Cardiol. 2000, 7: 43-52. 10.1067/mnc.2000.99189.View ArticlePubMedGoogle Scholar
- Pacella JJ: Circulation. 2006, 114: 1940-7. 10.1161/CIRCULATIONAHA.106.641779.View ArticlePubMedGoogle Scholar
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