- Meeting abstract
- Open Access
1086 Accurate quantification of simultaneous mitral and tricuspid blood flow using 3D velocity-encoded MRI with retrospective valve tracking
© Westenberg et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Tricuspid Valve
- Echo Planar Image
- Left Ventricular Filling
- Valve Regurgitation
- Aortic Flow
In valvular disease, surgical decision-making regarding timing and type of intervention is based on the severity of the regurgitation through the particular atria-ventricular valve. Conventional one-directional (1-dir) velocity-encoded (VE) MRI is routinely used for flow assessment over the mitral (MV) and tricuspid valve (TV), but this technique has been shown to be inaccurate and correlation between 1-dir VE MRI MV- and TV-flow measurement is weak.
Validation of three-dimensional (3D) 3-dir VE MRI with retrospective valve tracking during offline analysis for simultaneous MV and TV-flow assessment in phantoms and volunteers without valve regurgitation. The MRI technique is also applied to twenty heart failure patients with valve regurgitation.
MRI was performed on a 1.5 T Gyroscan ACS/NT15 (Philips, Best, the Netherlands). A 3D 3-dir VE MRI sequence (3D volume scan with slab thickness 48 mm, acquisition voxel size 2.9 × 3.8 × 4.0 mm3, velocity sensitivity 150 cm/s in all directions, with 30 phases reconstructed during one average cardiac cycle, with free breathing in vivo) was designed and tested in stationary flow phantoms and in a phantom simulating harmonic left ventricular filling. Echo Planar Imaging (EPI) was used for accelerating the acquisition (EPI factor 5, in vivo scan time <5 min).
Finally, MV and TV-flow was assessed in twenty patients with ischemic heart failure and MV and/or TV regurgition.
Although correlation for MV- and TV-flow with aortic flow was also good, these showed significant bias due to the aortic valve regurgitation that was present in several cases.
3D VE MRI provides the true trans-valvular MV and TV-flow in a single acquisition in less than 5 minutes scan time. Regurgitation through atrio-ventricular valves can be accurately quantified, providing essential information for surgical decision-making.
This article is published under license to BioMed Central Ltd.