- Meeting abstract
- Open Access
1090 Black-blood myocardial T2 and oxygenation imaging using a diffusion-weighted prepared sequence
© McCommis et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Leave Anterior Descend
- Limited Blood Flow
- Oxygen Extraction Fraction
- Coronary Sinus Blood
- Irregular Heart Rhythm
We have recently shown that blood-oxygen-level-dependent (BOLD) T2-weighted images can determine the myocardial oxygen extraction fraction (OEF) during hyperemia [1, 2]. This method works well using a double-inversion-recovery-pulse (DIR) prepared black-blood sequence. However, when irregular EKG-triggering or arrhythmias occur, for instance, during Dobutamine hyperemia, it is difficult to adequately suppress blood signal. The purpose of this study is to evaluate another black-blood imaging technique, a so called diffusion-weighted (DW)-prepared sequence , for its capability to determine the myocardial T2 and then quantify OEF in a stenotic dog model.
The disadvantages of the DW method are the lower SNR (6.6 ± 2.1%) compared with DIR images, as well as an increased sensitivity to the magnetic shimming.
The DW imaging method appears to perform well or better for the quantification of OEF, despite lower SNR. In clinical practice, adding DW prepared sequences in cardiac CMR protocols may provide quality black-blood images when irregular ECG-triggering or arrhythmias is presented.
- Zheng J, et al: Magn Reson Med. 2004, 51: 718-726. 10.1002/mrm.20025.View ArticlePubMedGoogle Scholar
- McCommis KS, et al: Magn Reson Imaging. 2007,Google Scholar
- Koktzoglou I, et al: J Cardiovasc Magn Reson. 2007, 9: 33-42. 10.1080/10976640600843413.View ArticlePubMedGoogle Scholar
- Zhang H, et al: J Magn Reson Imaging. 2007, 26: 72-9. 10.1002/jmri.20964.View ArticlePubMedGoogle Scholar
- Buck A, et al: J Nucl Med. 1991, 32: 1950-1957.PubMedGoogle Scholar
This article is published under license to BioMed Central Ltd.