- Meeting abstract
- Open Access
1141 Can every other heart-beat acquisition be better for the same breath-hold interval in MR tagging sequences?
© Basha et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Flip Angle
- Bloch Equation
- Phantom Experiment
- Spiral Acquisition
- Excitation Radiofrequency
In cardiac MRI with segmented k-space acquisition, data is partially acquired through consecutive cardiac cycles. However, the available longitudinal magnetization in a given cardiac cycle is exhausted by the excitation radiofrequency pulses in previous cycles, which limits the available signal-to-noise ratio (SNR). One potential solution is to increase the repetition time (TR) to allow for partial magnetization recovery between the RF pulses. However, this solution is not practical in sequences with breath-hold acquisition as it increases the breath-hold time, which limits the applicability of the considered sequence. In this work, a new technique is proposed for improving the SNR without increasing the breath-hold time. The idea is based on acquiring the signal every other heartbeat within the same breath-hold time interval. This limits the number of the acquired k-space segments to a half but allow the magnetization a longer time to recover. This technique results in better SNR, compared to conventional (every heartbeat) segmented k-space acquisition, as evidenced by numerical simulations of the Bloch equation as well as phantom and in-vivo experiments. Two tagging pulse sequences are considered in this work: complementary-spatial-modulation-of-magnetization (CSPAMM)  and strain-encoding (SENC) MRI .
Numerical simulations of the Bloch equation were conducted to examine the effect of the imaging flip angle and TR on the resulting signal amplitude. Ramped flip angle scheme was implemented [1, 3]. The simulations were conducted for both every heartbeat and every-other heartbeat acquisition schemes.
To verify the simulations, a phantom experiment was conducted using a spiral acquisition . Two sets of CSPAMM and SENC images were acquired using the same breath-hold intervals. In the first set, the acquisition was done every heartbeat while for the second set it was every-other heartbeat. To compensate for the number of spiral trajectories that was halved in the second set, two modifications were done. First, the spiral acquisition window time was doubled. Second, a multi-shot acquisition with factor 2 per cardiac phase was used.
In vivo studies
Two normal volunteers were consented and scanned using the same sequences. SNR was measured from the images by defining a region of interest in the static tissue and the heart. The noise was measured from the background and adjusted for Rayleigh distribution.
In contrast to what is usually performed in routinely conducted CSPAMM and SENC studies, we have demonstrated that for the same breath-hold time interval, the every-other heartbeat acquisition gives substantially higher SNR than every heart-beat acquisition. This should be taken into consideration for routinely conducted studies to improve the quality of the resulting images.
This work was supported in part by grants from the national institute of heart, lung and blood R01HL072704 and R01HL61912, and Donald W. Reynolds Foundation grant.
This article is published under license to BioMed Central Ltd.