- Meeting abstract
- Open Access
1143 Compressed sensing cardiac perfusion imaging: feasibility and comparison to k-t BLAST
© Vitanis et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Compressed Sensing
- Acceleration Factor
- Critical Acceleration
- High Acceleration Factor
- Joint Encode
In myocardial perfusion, several requirements must be met in order to acquire diagnostically meaningful data sets. The most important among them are: a) high temporal resolution, b) high spatial resolution and c) adequate coverage . However, as it is generally the case in dynamic MRI, there is a trade-off between the achievable temporal and spatial resolutions. In order to relax this trade-off and accelerate perfusion imaging, techniques which exploit either spatial  or spatiotemporal correlations [3, 4] have been proposed. Among them, the highest resolution in space and time was achieved when using k-t SENSE , which performs the reconstruction by exploiting the spatiotemporal redundancy present in perfusion images.
In this work, we investigate the potential of Compressed Sensing (CS)  as a method to accelerate perfusion imaging. Compressed Sensing has been proposed as a method to efficiently accelerate dynamic MRI (cine, angiography)  by exploiting the implicit sparsity of dynamic images. Model simulations demonstrate the feasibility of CS perfusion and compare the method to k-t BLAST, the single-coil version of k-t SENSE.
Nonlinear reconstruction methods for undersampled data feature interesting properties which can be exploited for accelerating perfusion imaging. Up to a certain critical acceleration factor (depending on the sparsity of the data and implicitly on the signal-to-noise ratio) this reconstruction is exact, resulting in high temporal fidelity comparable to that of the k-t BLAST reconstruction. It can be claimed, however, that perfusion imaging using any of the two methods and an acceleration beyond the critical one (~5×) is unreliable and techniques which exploit coil encoding as a joint encoding entity should be pursued [9, 10].
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