- Meeting abstract
- Open Access
2102 The ischemic area at risk can be detected by both T1 and T2 pre-contrast CMR
© Aletras et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Acute Myocardial Infarction
- Good Image Quality
- Normal Myocardium
- Ischemic Area
- Remote Myocardium
In-vivo T2-weighted CMR delineates the area at risk (AAR) and can be used in conjunction with delayed contrast enhancement to evaluate infarct reduction therapies.
We hypothesized that pre-gadolinium T1 CMR delineates the AAR in a similar manner to T2 imaging in acute myocardial infarction.
Imaging was performed 3 days after LAD occlusion-reperfusion in13 dogs. T2 and T1 maps were computed from pre-gadolinium CMR with T2-prepared SSFP (14 TE's of 16–280 ms) and with IR-GRE (10 TIs of 71–900 ms) respectively. The infarcted territory was defined by post-gadolinium delayed enhancement. Two observers evaluated the images for the involvement of a single coronary distribution, for graininess and border definition of different areas.
The area at risk, as identified by T2-CMR, was identified by pre-gadolinium T1-CMR. Both methods could identify the infarct from the peri-infarct zone and remote myocardium. Pre-gadolinium T1 had better image quality in all 13 cases.
This article is published under license to BioMed Central Ltd.