- Meeting abstract
- Open Access
2102 The ischemic area at risk can be detected by both T1 and T2 pre-contrast CMR
https://doi.org/10.1186/1532-429X-10-S1-A371
© Aletras et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
Keywords
- Acute Myocardial Infarction
- Good Image Quality
- Normal Myocardium
- Ischemic Area
- Remote Myocardium
Introduction
In-vivo T2-weighted CMR delineates the area at risk (AAR) and can be used in conjunction with delayed contrast enhancement to evaluate infarct reduction therapies.
Objectives
We hypothesized that pre-gadolinium T1 CMR delineates the AAR in a similar manner to T2 imaging in acute myocardial infarction.
Methods
Imaging was performed 3 days after LAD occlusion-reperfusion in13 dogs. T2 and T1 maps were computed from pre-gadolinium CMR with T2-prepared SSFP (14 TE's of 16–280 ms) and with IR-GRE (10 TIs of 71–900 ms) respectively. The infarcted territory was defined by post-gadolinium delayed enhancement. Two observers evaluated the images for the involvement of a single coronary distribution, for graininess and border definition of different areas.
Results
T1-CMR delineates the area at risk similarly to T2-CMR in acute myocardial infarction. Both T1 and T2 maps can differentiate the infarct from the peri-infarct zone and from remote myocardium. The T1 maps had better image quality than T2.
Conclusion
The area at risk, as identified by T2-CMR, was identified by pre-gadolinium T1-CMR. Both methods could identify the infarct from the peri-infarct zone and remote myocardium. Pre-gadolinium T1 had better image quality in all 13 cases.
Authors’ Affiliations
Copyright
This article is published under license to BioMed Central Ltd.
