- Meeting abstract
- Open Access
139 Determination of myocardial OEF with a CMR method in a stenotic dog study
© McCommis et al; licensee BioMed Central Ltd. 2008
- Published: 22 October 2008
- Cardiovascular Magnetic Resonance
- Oxygen Extraction Fraction
- Double Inversion Recovery
- Perfusion Cardiovascular Magnetic Resonance
Recently, we have shown that a CMR method can non-invasively determine the oxygen extraction fraction (OEF) in dogs during hyperemia [1, 2] with assumed myocardial blood volume (MBV) values. The purpose of this study is to determine the effect of quantified MBV to the calculation of myocardial OEF during pharmacologically induced hyperemia in coronary artery stenotic dogs.
Table of dog groups.
Using the two-compartment model and CMR methods, the effect of MBV quantification is subtle in the calculation of myocardial OEF. In dogs with varying severities of coronary artery stenosis, regional differences in OEF during the hyperemia can be readily detected using this CMR method.
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