- Oral presentation
- Open Access
Three-dimensional measurement of LV and RV dimensions using prospective self-gating for simultaneous compensation of cardiac and respiratory motion
© Manka et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Right Ventricular
- Left Ventricular Mass
- Image Quality Score
- Lower Image Contrast
- Cine Sequence
To compare three-dimensional (3D) balanced steady-state free precession (SSFP), prospective self-gating technique  without ECG triggering and breath-holding for the assessment of left ventricular (LV) and right ventricular (RV) function in the heart in comparison to standard 2D, multiple breath-hold SSFP cine imaging.
Data were acquired in 15 subjects (10 volunteers, 5 patients) using a 1.5 T system with a five element cardiac array coil. In each subject a standard multi-slice, multi-breathhold 2D cine SSFP sequence was performed with complete ventricular coverage. Additionally, a three-dimensional cine sequence with prospective self-gating  with complete ventricular coverage was acquired during free breathing. LV and RV end-systolic volume (ESV) and end-diastolic volume (EDV) and LV mass were calculated for each method. With both imaging techniques, a patient-based analysis of image quality was performed with grading on a four-point scale, referring to the visibility of the endocardial border (excellent (4), good (3), moderate (2) and nondiagnostic (1)).
Three-dimensional, free-breathing, prospective self-gating MRI enabled accurate assessment of LV and RV quantitative parameters when compared to standard multi-slice, multi-breathhold SSFP cine imaging. Image quality with prospective self-gating was rated lower relative to the reference ECG triggered, multiple breathhold scans due to lower image contrast between blood and myocardium and residual motion artefacts.