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Impact of myocardial hemorrhage on left ventricular function and remodeling in patients with reperfused acute myocardial infarction
© Ganame et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Left Ventricular Ejection Fraction
- Infarct Size
- Left Ventricular Volume
- Microvascular Obstruction
- Cine Magnetic Resonance Imaging
Myocardial hemorrhage is a common complication following reperfusion of ST-segment-elevation acute myocardial infarction (MI). Although its presence is clearly related to infarct size, at present it is unknown whether post-reperfusion hemorrhage affects left ventricular (LV) remodeling. Magnetic resonance imaging (MRI) can be used to identify myocardial infarction, myocardial hemorrhage and microvascular obstruction (MVO), as well as measure LV volumes, function and mass.
Results of multiple linear regression of left ventricular remodeling
Predictors of end point
Infarct size at baseline
Maximum troponin I
Size of area at risk
LV mass at baseline
Percent MI transmurality
Time to PCI
Myocardial hemorrhage, the presence of which can easily be detected with T2-weighted MRI, is a frequent complication after successful myocardial reperfusion, and an independent predictor of adverse LV remodeling regardless of initial infarct size.
This article is published under license to BioMed Central Ltd.