k-t SENSE accelerated stress myocardial perfusion MRI at 3 Tesla
© Kato et al; licensee BioMed Central Ltd. 2009
Published: 28 January 2009
The purpose of this study was to evaluate the feasibility and diagnostic accuracy of high spatial resolution stress myocardial perfusion MRI acquired at every heartbeat by using k-t SENSE and 3 Tesla MR imager.
High spatial and temporal resolutions are required for the accurate assessment of myocardial ischemia using stress perfusion MRI.
Thirty-three patients with suspected coronary artery disease were studied. High spatial resolution (<2 mm) first-pass contrast enhanced MR images were obtained at rest and during stress by using a 3.0 T MR imager (Achieva) and k-t SENSE acceleration factor of 5. Saturation recovery TFE images were acquired with TR/TE of 2.9 ms/1.5 ms, FOV = 40 × 30 cm, matrix = 256 × 192, slice thickness = 8 mm. Three short-axis sections of the left ventricle were imaged at every heart beat. Two observers determined the image quality score (1:poor – 4:excellent) and recorded the presence or absence of respiratory artifacts and endocardial dark rim artifacts using a 16-segment model.
Perfusion MR images with high spatial resolution can be acquired at every heart beat by using a 3 T MR imager and k-t SENSE acceleration. This approach can substantially reduce endocardial dark rim artifacts and allows for an accurate detection of myocardial ischemia in patients with flow-limiting coronary artery disease.
This article is published under license to BioMed Central Ltd.