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Improved accuracy in flow mapping of congenital heart disease using stationary phantom technique


We aimed to define the differences between flow mapping with and without baseline correction using a stationary phantom when evaluating congenital heart disease (CHD).


Flow mapping by cardiovascular magnetic resonance (CMR) has become the gold standard for defining cardiac output, shunt flow and regurgitation. Previous reports have highlighted the presence of inherent errors in flow mapping by CMR secondary to eddy currents and concomitant gradients. The use of a stationary phantom to control for these errors can improve predicted Qp/Qs ratios in normal volunteers. To our knowledge, no one has investigated the effect of phantom correction in CHD.


All patients were imaged using GE 1.5 T Signa HDX systems. Phase velocity flow mapping by CMR was performed when clinically indicated on 20 patients with repaired Tetrology of Fallot (ToF), 7 patients with atrial level shunting (ASD/PAPVR), and 13 patients with bicuspid aortic valves (BAV). Flow velocities through the ascending aorta, main pulmonary artery (MPA) and proximal branch pulmonary arteries (BPA) were calculated using commercially available software (ReportCard) by placing a region of interest (ROI) around the vessel lumen. Flow velocities were then corrected by measuring baseline velocities in a ROI of the same size and location on a corresponding stationary phantom image. Comparison was then made between the uncorrected and corrected flows, degree of shunting, and regurgitant fraction. Qp/Qs was calculated as the ratio of net BPA flow to aortic flow.


Marked variation in net flow was seen in all vessels (Table 1). The variation in net flow was largest when analyzing the MPA/RVOT with a range of 0.2 to 70 ml/min (0.3–107.5% difference). In repaired ToF patients, the average Qp:Qs ratio was 1.03 with phantom correction and 1.15 without. Based on previously published criteria, 26% of the ToF group would have been incorrectly classified as having a residual shunt without performing phantom correction. In the ASD/PAPVR group 100% had significant shunting with phantom correction, while only 71% of uncorrected flows detected significant shunting. In the BAV group, the differences in the regurgitant fraction ranged from 0 to 31%. 23% of the patients changed their classification between mild, moderate and severe regurgitation when the phantom was performed.

Table 1 Differences in net flows between corrected and uncorrected flow mapping


The impact of inherent errors in CMR flow mapping should not be underestimated. The range of variation, in common CHD, appears large and varied. Failure to correct for such variation can lead to clinically significant misinterpretation of flow data. The use of the stationary phantom correction technique appears to improve flow accuracy in patients with CHD. Further research is needed to elicit the causes and best control of such errors.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution 2.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Miller, T.A., Moran, A.M. Improved accuracy in flow mapping of congenital heart disease using stationary phantom technique. J Cardiovasc Magn Reson 11 (Suppl 1), P102 (2009).

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