- Poster presentation
- Open Access
Comparison between single shot ir-steady state free precession and conventional ir-fast gradient echo sequence for automated quantification of the scar size in acute myocardial infarction in daily practice
© Kirchhartz et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Image Quality
- Acute Myocardial Infarction
- Motion Artifact
- Daily Practice
- Automate Analysis
For scar quantification of acute myocardial infarction traditionally an inversion recovery fast gradient echo sequence is used. During the last years a single shot IR steady state free precession sequence was introduced as an alternative. We performed this study to compare the robustness of both sequences on critically ill patients in daily practice.
97 consecutive patients with acute myocardial infarction (interval between start of symptoms and intervention below 24 h) undergoing cardiac MRI for quantification of the scar size between October 2006 and October 2007 were included into the study. After application of 0.2 mmol/kg body weight gadopentetate dimeglumine both a standard IR-fast gradient echo sequence and a single shot IR steady state free precession sequence were performed. Image quality was assessed semiquantitatively by two experienced readers using a score ranging from 0 (nondiagnostic) to 5 (excellent). On all images with a score of at least 2 (fair, suitable for automated analysis), the signal intensity of the scar and of a remote region was measured. In addition the scar size was quantified automatically using a cutoff of mean plus 4 standard deviations (sd) of the signal intensity in the remote region.
The new single shot IR-steady state free precession sequence is more robust against motion artifact, when compared with the standard IR-fast gradient echo sequence. Both sequences show a similar contrast to noise and signal to noise ratio. They correlate well on direct comparison.
This article is published under license to BioMed Central Ltd.