- Poster presentation
- Open Access
Diagnostic accuracy of high-temporal resolution whole heart coronary magnetic resonance angiography at 3.0 Tesla
© Motonori et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Significant Coronary Artery Disease
- Average Heart Rate
- Branch Vessel
- Image Quality Score
- Acquisition Window
30 T whole heart coronary MR angiography permits acquisition of coronary arterial images with improved signal to noise ratio and high spatial resolution. The use of a patient-specific, narrow acquisition window in the cardiac cycle can reduce motion blurring on coronary MR angiography, and may allow for improved delineation of distal coronary arteries and branch vessels.
The purpose of this study was to determine the image quality and diagnostic accuracy of 3.0 T whole-heart coronary MR angiography acquired with a subject-specific, narrow acquisition window in the cardiac cycle.
Free breathing whole heart coronary MR angiograms were acquired in 32 patients with suspected coronary artery disease by using a 3.0 T MR imager and 6 channel cardiac coil system. After administration of gadolinium contrast medium, navigator-echo gated, 3-dementional TFE images were obtained with T2 preparation, fat saturation, TR/TE/FA of 4.2 ms/2.1 ms/20 degree and SENSE factor of 2. A narrow data acquisition window in the cardiac cycle was used by monitoring motion of the coronary arteries on cine MRI in each patient. MRA data were acquired during diastole in 22 patients (averaged heart rate = 65.5 ± 8.2 beat/min, acquisition window = 63 ± 25 ms), and during systole in 10 patients (averaged heart rate = 75.1 ± 10.3 beats/min, acquisition window = 36.2 ± 6.2 ms). Image quality was classified on a 4-point scale (1 = poor, 2 = moderate, 3 = good, 4 = excellent). X-ray coronary angiograms were obtained in 11 patients within 2 weeks from MR study. Significant coronary artery disease was defined as a diameter reduction of ≥ 50 % in coronary arteries with a reference of ≥ 2 mm on X-ray coronary angiography. MRA images were interpreted by 2 independent observers by using a sliding multiplanar reformat reconstruction method, and disagreement between 2 observers was settled by a consensus reading.
30 T free-breathing whole heart coronary MR angiography acquired with a subject-specific, narrow acquisition window in the cardiac cycle permits improved visualization of coronary arteries including distal segments and branch vessels. High negative predictive value found in this study indicates the value of 3.0 T coronary MRA for screening significant coronary artery disease.
This article is published under license to BioMed Central Ltd.