- Poster presentation
- Open Access
Evaluation of model-based contouring versus 2D segmentation for cardiac mass and volumes
© Chi et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Left Ventricular Mass
- Myocardial Mass
- Peak Filling Rate
- Peak Ejection Rate
- SSFP Cine
To compare three-dimensional, model-based contouring versus two-dimensional, semi-automatic contouring of cardiac cine MRI for determination of left ventricular mass and volumes.
Traditional cardiac MRI methods have relied on slice-by-slice contouring and mathematical calculations to estimate myocardial mass and volumes. Three-dimensional model-based algorithms offer the potential advantages of faster analysis times, increased reproducibility, and physiologically-relevant information that includes the complex motion of the mitral valve, balanced by potential sensitivity to slice misregistration related to multiple breath-holds.
100 cardiac MRI SSFP cine studies were evaluated using a model-based software (Cardiac Image Modeller (CIM)) and a semiautomatic contouring system (MASS). Parameters of cardiac function included left ventricular (LV) end diastolic mass (EDM), end diastolic volume (EDV), end systolic volume (ESV), and ejection fraction (EF). Peak ejection rate (PER) and peak filling rate (PFR) were also included. Reproducibility data for intra-observer variability was performed for 20 consecutive cases.
Compared to two-dimensional contouring techniques for cardiac MRI analysis, model-based contouring provides a reliable alternative for quantitative determination of myocardial mass and volumes. Characterization of systolic emptying and diastolic filling rates varies significantly between the two methods; further study is needed to understand these differences.
This article is published under license to BioMed Central Ltd.