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Correlation between velocity encoded cine magnetic resonance imaging and Doppler echocardiography for the evaluation of diastolic dysfunction

  • Ijaz Ahmad1,
  • Mitra Sahebazamai1,
  • Lesan Banko1,
  • Joshua A Sockolow1,
  • Igor Klem2,
  • Terrence Sacchi1 and
  • John F Heitner1
Journal of Cardiovascular Magnetic Resonance200911(Suppl 1):P37

Published: 28 January 2009


Leave Ventricular Ejection FractionPulmonary VeinCardiac Magnetic ResonanceVentricular EjectionDiastolic Dysfunction


Doppler echocardiographic (Echo) measurements of the mitral and pulmonary venous flow have been used to assess diastolic dysfunction (DD). Velocity-encoded cardiac magnetic resonance (Ve-CMR) can measure similar parameters and may potentially be used for the assessment of DD.


To assess the correlation of Ve-CMR with Echo in assessing mitral inflow E/A ratio, left atrial (LA) size, and pulmonary vein (PV) flow.


We prospectively enrolled 22 outpatients with a mitral inflow pattern by Echo that was normal (8), impaired relaxation (7), pseudo-normal (2), or restrictive (5). The mean left ventricular ejection fraction (LVEF) was 60.8 and two patients had left ventricular hypertrophy on echo. Ve-CMR was performed within 2 hours of the Echo. The following indices were measured: LA size, mitral inflow E-velocity (E), A-velocity (A), E/A ratio, PV waves (S, D and A).


The mean age of the patients was 51 years. The average Echo mitral inflow absolute velocities were close to double the Ve-CMR {Echo E-velocity = 85.8 cm/sec vs. Ve-CMR E velocity = 41.4 cm/sec, Echo A-velocity 70 cm/sec vs. Ve-CMR A-velocity 32.5 cm/sec}. The average E/A ratio was 1.41 by echocardiogram and 1.48 by Ve-CMR. There was a significant correlation in LA size and Mitral inflow E/A ratio between Ve-CMR and Echo (Rho = 0.9, p < 0.01; Rho = 0.88, p < 0.01, respectively). There were no significant correlations in PV waves (Rho = 0.12, p = 0.58). Figure 1
Figure 1
Figure 1

Correlation between Ve-CMR and Doppler echo derived values was tested using Spearman's rank correlation coefficients. There was significant correlation between left atrial size and E/A ratio. A: LA size (R = 0.9, p-value < 0.05), B: E/A ratio (R = 0.88, p-value < 0.05), but not C: (R = 0.12, p = 0.58). LA; left atrium, PV, pulmonary vein.


Ve-CMR has a very high correlation with Echo in the assessment of mitral inflow E/A ratio and LA size. Ve-CMR maybe useful for the assessment of diastolic dysfunction.

Authors’ Affiliations

New York Methodist Hospital, Brooklyn, USA
Duke University Medical Center, Durham, USA


© Ahmad et al; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.