- Poster presentation
- Open Access
Evaluation of complex congenital heart disease and associated complications in newborns, infants and small children using multi-detector CT
© Eichhorn et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Congenital Heart Disease
- Vascular Anomaly
- Complex Congenital Heart Disease
- Arterial Ring
- Minimize Radiation Exposure
Multi-detector CT (MDCT) with multiplanar and three-dimensional (3D) reconstruction has become an important first-line imaging tool in diagnosis of congenital vascular anomalies (VA) and airway diseases in children.
To assess the diagnostic value of MDCT for evaluation of VA and associated complications in newborns and infants.
At 4 centers, 262 children (mean age: 7 ± 7 months, range: 6 hours to 24 months) were examed. The diagnoses included: suspected of having in-stent stenosis after stent placement to treat vascular stenoses (n = 72), pulmonary atresia (32) and stenosis (48) with collateral arteries, arterial rings and slings (28), aortic arch anomalies (15), bronchoscopy revealed stenosis(23), abnormal pulmonary venous return (15) and others (29). The CT exams were performed on varying scanners (4 up to 64 slices, collimation isotrope 0.4–1.25 mm; scan-time 2–20 s, usage of low dose protocols: 80–120 kVp, 60–80 mA) under controlled ventilation or free breathing, mostly without ECG-gating to minimize radiation exposure. The image quality was rated using a 5-point score. Image findings were correlated to echocardiography, conventional digital catheter angiography (DA), bronchoscopy, and intraoperativ findings. The effects of dose on image quality were also evaluated, retrospectively.
A 3D submillimeter evaluation of the heart and great vessels can be achieved routinely in a matter of seconds with little motion artifacts, without general anesthesia and with much less radiation exposure than previously thought. Nevertheless, the optimal radiation dose settings for performing cardiac CT in infants and pediatric patients are still being worked out. The use of CT for screening may result in a net decrease in overall radiation decreasing the number of diagnostic cardiac catherizations. CT can now be regarded as the modality of choice as a minimally invasive, robust, and accurate technique for the diagnosis of complex VA even in the group of newborns and infants or critically ill patients. Its accuracy for detecting VA appears at least equivalent to catherizations while it is more accurate in delineating potential life-threatening complications. This advance should have the greatest impact in the smallest, youngest, and most critically ill children with congenital heart disease.
This article is published under license to BioMed Central Ltd.