- Poster presentation
- Open Access
Effective fat-suppression for late gadolinium enhancement combined with a sequential acquisition order
© Peters et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Late Gadolinium Enhancement
- Mitral Valve Prolapse
- Centric Order
- Adiabatic Pulse
- Acquisition Order
Fat suppression is valuable for late gadolinium enhancement (LGE) imaging, for situations in which an enhanced structure is adjacent to fat (e.g. myocardium at the apex of the left ventricle, vessel walls, and the thin atrial walls), where fat might be mistaken for fibrosis. However, the acquisition order of the segmented LGE sequence is also critical, and a sequential acquisition order is superior to a centric acquisition order when visualizing small areas of scar, in which the "edge-enhancement" (i.e. the stronger weighting of the edges of k-space due to signal regrowth during the acquisition window) effect is not desired. A fat-suppressed LGE sequence using a sequential acquisition order may be optimal, but is not feasible using the typical fat-selective (spectrally-selective) RF pulse with a flip angle from 90° to 180° preceding the sequential acquisition. To address this, we developed a "fat restore" method for fat-suppressed LGE.
We have demonstrated that the fat-restore pulse improves fat-suppression for sequentially acquired LGE scans. Studies with 3D LGE will likely improve with the linear acquisition order, improving the confidence for detecting small regions of scar.
This article is published under license to BioMed Central Ltd.