Evaluation of myocardial function after primary percutaneous intervention by cardial MRI: 5 years follow up
© Springeling et al; licensee BioMed Central Ltd. 2009
Published: 28 January 2009
We investigated the early and late effect of primary percutaneous coronary interventions (PCI) for acute myocardial infarction on recovery of left ventricular ejection fraction (LVEF), end diastolic volume (EDV), end systolic volume (ESV) and segmental wall thickening (SWT) using Cardiac MRI.
This abstract includes preliminary analysis of the first 12 patients. All patients underwent cardial MRI within 5 days, at 5 months and at 5 years after successful primary PCI. LVEF, EDV, ESV and SWT quantified on cine-images, the transmural extent of the infarction (TEI) was quantified on delayed-enhancement images.
SWT improved significantly between baseline and 5 months follow up (from 23% to 30%, p = 0.04), no additional improvement was seen at 5 years (SWT 33%, p = 0.29). TEI at baseline showed a good correlation with SWT at 5 months and 5 years follow up.
These interesting preliminary results of 12 patients indicates a tendency to late remodelling at 5 years follow up by which LVEF is preserved. TEI at baseline predicted regional SWT at follow up.
This article is published under license to BioMed Central Ltd.