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Acquiring multiple slices in a single breath-hold. Is it practical for routine workflow?
© Wage et al; licensee BioMed Central Ltd. 2009
- Published: 28 January 2009
- Cardiovascular Magnetic Resonance
- Ventricular Volume
- Free Precession
- Single Slice
- Steady State Free Precession Sequence
The acquisition of the ventricular short axis cine stack forms the backbone of the routine cardiovascular magnetic resonance scan . From this, the left and right ventricular volumes are calculated and important information is gained about wall thickness, regional function and evidence of dyssynchrony. Steady-state free precession cine (SSFP) loops can take between 8 and 12 seconds each to acquire and traditionally, a single breath-hold has been required for each slice. Parallel imaging technology has allowed reduction in the time taken for each acquisition without a significant drop in signal-to-noise ratio. As a consequence, it is possible to acquire two slices for each breath-hold. The scanner can be easily programmed to acquire a set of equally spaced ventricular short axis slices .
The purpose of this study was to assess the practicality of using a two-slice per breath-hold ventricular short axis cine sequence in routine daily practice.
From the beginning of March 2008 to September 2008, we used a two-slice per breath-hold steady state free precession sequence to acquire the ventricular short axis stack of cines in a total of 478 patients. All patients were scanned with a 1.5 T Siemens scanner (Sonata or Avanto, Siemens, Erlangen, Germany) using anterior phased-array coils and ECG gating. Sequence parameters for the SSFP cine were as follows: 2 slices (8 mm slice thickness), 25% distance factor (2 mm gap), TR 40.2 ms, TE 1.13 ms, flip angle 80°, base resolution 192, number of signal averages 1, parallel imaging (GRAPPA; generalised autocalibrating partial parallel acquisition), bandwidth 930 Hx/Px, echo spacing 2.7 ms. Ten patients had both two-slice and single slice per breath-hold cine stack acquired. The parameters for the single slice acquisition were identical to those given above apart from using a 7 mm slice thickness with 3 mm gap.
Coefficient of variation between scan techniques for single-slice and two-slice per breath-hold acquistion.
Mean difference between techniques (+/- in brackets)
Average coefficient of variation (%)
LV end-diastolic volume (ml)
LV end-systolic volume (ml)
Stroke volume (ml)
LV mass (g)
Ejection fraction (%)
In conclusion, the use of a two-slice per breath-hold cine acquisition is a practical method for use in daily practice. This shortens the time required for the whole ventricular short axis cine stack and allows a streamlining of workflow with overall reduction in the time taken for each CMR study. There is no significant difference in the ventricular volumes, mass or ejection fraction calculated.
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This article is published under license to BioMed Central Ltd.