- Oral presentation
- Open Access
Weight reduction surgery is associated with substantial long term reduction in left ventricular mass
© Banerjee et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Uncomplicated obesity is associated with left ventricular hypertrophy, which is an independent risk factor for cardiovascular events. Excess body weight has a linear relationship with vascular mortality. We have previously shown that weight reduction surgery is associated with LV mass reduction 1 year later. Here we have used CMR to investigate the effects of weight reduction surgery at 3 years.
We followed up 6 patients who had undergone Roux-en-Y gastric bypass surgery for obesity (Body Mass Index 46.7 ± 3.8 kg/m2). All subjects had no other identifiable cardiovascular risk factors: diabetes, hypertension, hypercholesterolaemia, smoking, obstructive sleep apnoea or known cardiac disease. The subjects had CMR scans (1.5 Tesla, Siemens, Erlangen, Germany) and body composition analysis performed at baseline, 1 and 3 years.
Over 3 years, weight reduction surgery is associated with a significant progressive reduction in LV mass, which continues even after BMI has stabilised after 1 year. This represents long-term LV remodelling in response to marked weight loss.
This article is published under license to BioMed Central Ltd.