- Oral presentation
- Open Access
Rapid right ventricular pacing with mr-compatible pacemaker lead for magnetic resonance-guided aortic balloon valvuloplasty in swine
© Neizel et al; licensee BioMed Central Ltd. 2010
- Published: 21 January 2010
- Aortic Valve
- Pericardial Effusion
- Myocardial Damage
- Ventricular Pace
- Rapid Pace
To assess the feasibility of rapid right ventricular pacing with a Magnetic Resonance (MR)-compatible pacemaker lead during MR-guided aortic valvuloplasty.
The feasibility of MR-guided aortic valvuloplasty in animal models has been demonstrated. However, to translate this MR-guided procedure into humans rapid pacing has to be performed to provide balloon stability.
6 pigs (weight 48 ± 3 kg) were investigated. All experiments were performed using an interventional 1.5 Tesla MRI system. Interventions were monitored using a steady-state free precession real-time imaging sequence. Parameters of the sequence were TR/TE = 2.5/1.25 ms, flip angle 45°, slice thickness 8 mm, matrix 128 × 128 reconstructed to 256 × 256 using zero-filling. A MR-compatible pacemaker lead was placed in the right ventricular apex under fluoroscopic MR-guidance before the valvuloplasty. After positioning of the balloon into the left ventricular outflow tract/aortic valve valvuloplasty was performed under rapid right ventricular pacing at a heart rate of 180 bpm to minimize cardiac output. For improved visualization the balloon was filled with Resovist.
Rapid right ventricular pacing with MR-compatible pacemaker lead is feasible and effective. The balloon remained in stable position during the critical phase of the procedure. This study demonstrates that MR-guided aortic valve balloon valvuloplasty may soon become reality in humans.
This article is published under license to BioMed Central Ltd.