- Oral presentation
- Open Access
Closed chest transthoracic perventricular ventricular septal defect closure under real-time MRI
© Ratnayaka et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Muscular ventricular septal defect (VSD) is common, and can be congenital, post-infarction, or post-traumatic. Real-time MRI can provide surgical-grade exposure for non-surgical procedures. One innovative pediatric surgical procedure is device closure of ventricular septal defect using catheter techniques through an open chest. We attempt to conduct this same procedure in a closed chest model using real-time MRI.
We hypothesize real-time MRI could guide closed chest transthoracic perventricular VSD device closure on beating hearts in swine without cardiopulmonary bypass or thoracotomy.
Real-time cardiac MRI permitted transthoracic perventricular VSD device closure and then free wall repair. There were no procedural complications including conduction or rhythm abnormalities, atrioventricular or semilunar valvular regurgitation, or device embolization. Small procedural effusions were drained with temporary pericardial catheters. Necropsy confirmed optimal device placement.
Transthoracic MRI guided perventricular muscular VSD closure is feasible in a porcine model, and has the potential to avoid cardiopulmonary bypass (traditional VSD surgical repair) or even sternotomy (hybrid perventricular approach). It is a radiation sparing alternative for small children in whom percutaneous options are risky or not possible.
This article is published under license to BioMed Central Ltd.